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NCT02777931 · ClinicalTrials.gov registry record · Phase 2

Efficacy and Safety of NFC-1 in Adolescents With Genetic Disorders Impacting mGluR and ADHD

A Phase 2 study of Attention Deficit Disorder With Hyperactivity, sponsored by Aevi Genomic Medicine, LLC, a Cerecor company.

Completed
Registry status
Phase 2
Development phase
101
Enrollment target
1
Study location

NCT02777931: Completed Phase 2 study of Attention Deficit Disorder With Hyperactivity, sponsored by Aevi Genomic Medicine, LLC, a Cerecor company.

NCT02777931 is a Phase 2 study of Attention Deficit Disorder With Hyperactivity that has completed, run by Aevi Genomic Medicine, LLC, a Cerecor company. The registered enrollment target is 101 participants, below the 350-participant average among 20 other Attention Deficit Disorder With Hyperactivity trials with a reported enrollment target (71% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02777931, a Phase 2 study of Attention Deficit Disorder With Hyperactivity, has completed, sponsored by Aevi Genomic Medicine, LLC, a Cerecor company.

COMPLETED
Registry status
Phase 2
Development phase
101 participants
Enrollment target
1
Study location

Study Summary

This is a randomized, double-blind, placebo-controlled, parallel-group study of NFC-1 versus placebo in adolescents with ADHD who have genetic disorders impacting mGluRs.

Primary Outcome

The ADHD-RS-5 is comprised of 18 frequency items and 12 impairment items. Each frequency item was scored on a scale from 0 = "Never or rarely" to 3 = "Very often". The ADHD-RS-5 total score was calculated as the sum of the 18 frequency item scores. The total score ranges from 0 to 54. Higher scores indicate greater symptom severity. Change from baseline value were calculated as the assessment value minus the baseline value.

Interventions

  • DRUG Placebo
  • DRUG NFC-1

Study Locations (1)

Maryland

  • The Clinical Trials Center at Kennedy Krieger Institute - Baltimore

Trial Details

FieldValue
Enrollment Target 101 participants
Start Date 2016-06
Est. Completion 2017-02-17
Phase Phase 2

What the finished NCT02777931 record still lists

NCT02777931 is an interventional study that assigns participants to a tested intervention. The registered 101 participants enrollment target is mid-sized for trials with a published cap, below the 350-participant average among 20 other Attention Deficit Disorder With Hyperactivity trials with a reported enrollment target (71% lower).

The record links to 1 condition, with Attention Deficit Disorder With Hyperactivity appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT02777931 reports a single indexed study location in Maryland.

Frequently Asked Questions

What is clinical trial NCT02777931 about?

NCT02777931 is a clinical study titled "Efficacy and Safety of NFC-1 in Adolescents With Genetic Disorders Impacting mGluR and ADHD". This is a randomized, double-blind, placebo-controlled, parallel-group study of NFC-1 versus placebo in adolescents with ADHD who have genetic disorders impacting mGluRs.

What is the current status of trial NCT02777931?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 101 participants. The study started on 2016-06. Estimated completion is 2017-02-17.

What conditions does trial NCT02777931 study?

This clinical trial studies the following conditions: Attention Deficit Disorder With Hyperactivity.

What interventions are being tested in trial NCT02777931?

The interventions under investigation include: Placebo (DRUG), NFC-1 (DRUG).

Who is sponsoring clinical trial NCT02777931?

This trial is sponsored by Aevi Genomic Medicine, LLC, a Cerecor company, which has 10 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02777931 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Attention Deficit Disorder With Hyperactivity

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02777931's enrollment target sits among peer trials

101 11th of 20 higher than 10 of 20 other Attention Deficit Disorder With Hyperactivity trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Attention Deficit Disorder With Hyperactivity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02777931, the US trial registry maintained by the National Library of Medicine. NCT02777931 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.