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NCT02777073 · ClinicalTrials.gov registry record · NA

Effects of Single Doses of Liraglutide and Dapagliflozin on Ketogenesis in Type 1 Diabetes

A NA study, sponsored by University at Buffalo.

Completed
Registry status
NA
Development phase
43
Enrollment target

NCT02777073: Completed NA study, sponsored by University at Buffalo.

NCT02777073 is a NA study that has completed, run by University at Buffalo. The registered enrollment target is 43 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02777073, a NA study, has completed, sponsored by University at Buffalo.

COMPLETED
Registry status
NA
Development phase
43 participants
Enrollment target

Study Summary

1. To compare levels of ketone bodies (beta-hydroxybutyrate and acetoacetate) in plasma and urine following a single dose treatment of either liraglutide 1.8mg, dapagliflozin 10mg or placebo in insulinopenic state. 2. To compare plasma levels of free fatty acid, glucagon, hs-CRP, Ll-6 and IL-1 before and after administration of liraglutide/placebo.

Primary Outcome

To compare levels of ketone bodies beta-hydroxybutyrate in plasma following a single dose treatment of either liraglutide 1.8mg,dapagliflozin 10mg or placebo in insulinopenic state.

Interventions

  • DRUG Placebo
  • DRUG Dapagliflozin 10mg Tab
  • DRUG Victoza

Trial Details

FieldValue
Enrollment Target 43 participants
Start Date 2016-03-01
Est. Completion 2016-12-31
Phase NA
University at Buffalo

67 total trials

What the finished NCT02777073 record still lists

NCT02777073 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 43 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT02777073 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02777073 about?

NCT02777073 is a clinical study titled "Effects of Single Doses of Liraglutide and Dapagliflozin on Ketogenesis in Type 1 Diabetes". 1. To compare levels of ketone bodies (beta-hydroxybutyrate and acetoacetate) in plasma and urine following a single dose treatment of either liraglutide 1.8mg, dapagliflozin 10mg or placebo in insulinopenic state. 2. To compare plasma levels of free fatty acid, glucagon, hs-CRP, Ll-6 and IL-1 befor...

What is the current status of trial NCT02777073?

This trial is currently completed. It is a NA study. The enrollment target is 43 participants. The study started on 2016-03-01. Estimated completion is 2016-12-31.

What interventions are being tested in trial NCT02777073?

The interventions under investigation include: Placebo (DRUG), Dapagliflozin 10mg Tab (DRUG), Victoza (DRUG).

Who is sponsoring clinical trial NCT02777073?

This trial is sponsored by University at Buffalo, which has 67 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02777073's enrollment target sits among peer trials

43 1435th of 2000 higher than 565 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02777073, the US trial registry maintained by the National Library of Medicine. NCT02777073 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.