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NCT02772081 · ClinicalTrials.gov registry record · Phase 3

A Study in Preterm Neonates With Respiratory Distress Syndrome (RDS) Comparing CUROSURF® Administration Through Less Invasive Surfactant Administration (LISA) and Conventional Administration

A Phase 3 study, sponsored by Chiesi Farmaceutici S.p.A..

Terminated
Registry status
Phase 3
Development phase
33
Enrollment target

NCT02772081 is a Phase 3 study that was terminated before completion, run by Chiesi Farmaceutici S.p.A.. The registered enrollment target is 33 participants.

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The verdict

NCT02772081, a Phase 3 study, was terminated before completion, sponsored by Chiesi Farmaceutici S.p.A..

TERMINATED
Registry status
Phase 3
Development phase
33 participants
Enrollment target

Study Summary

This study compared the administration of porcine surfactant (poractant alfa, Curosurf®) through a less invasive method (LISA), using a thin catheter, CHF 6440 (LISACATH®), during non-invasive ventilation (CPAP, NIPPV, BiPAP) with an approved conventional surfactant administration during invasive ventilation followed by rapid extubation in terms of short term and mid-term safety and efficacy in spontaneously breathing preterm neonates who have clinical signs of respiratory distress syndrome (RDS).

Interventions

  • COMBINATION_PRODUCT LISA combination product (Curosurf+catheter CHF6440)
  • DRUG Curosurf through conventional administration (endotracheal tube)

Trial Details

FieldValue
Enrollment Target 33 participants
Start Date 2021-05-18
Est. Completion 2022-08-13
Phase Phase 3

Sponsor

Chiesi Farmaceutici S.p.A.

30 total trials

What the Registry Record Tells You About NCT02772081

The ClinicalTrials.gov registry entry for NCT02772081 describes a study currently listed as terminated, categorized as Phase 3. The registered enrollment target is 33 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Chiesi Farmaceutici S.p.A., which has 30 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which LISA combination product (Curosurf+catheter CHF6440) is the first listed.

NCT02772081 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02772081 about?

NCT02772081 is a clinical study titled "A Study in Preterm Neonates With Respiratory Distress Syndrome (RDS) Comparing CUROSURF® Administration Through Less Invasive Surfactant Administration (LISA) and Conventional Administration". This study compared the administration of porcine surfactant (poractant alfa, Curosurf®) through a less invasive method (LISA), using a thin catheter, CHF 6440 (LISACATH®), during non-invasive ventilation (CPAP, NIPPV, BiPAP) with an approved conventional surfactant administration during invasive ve...

What is the current status of trial NCT02772081?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 33 participants. The study started on 2021-05-18. Estimated completion is 2022-08-13.

What interventions are being tested in trial NCT02772081?

The interventions under investigation include: LISA combination product (Curosurf+catheter CHF6440) (COMBINATION_PRODUCT), Curosurf through conventional administration (endotracheal tube) (DRUG).

Who is sponsoring clinical trial NCT02772081?

This trial is sponsored by Chiesi Farmaceutici S.p.A., which has 30 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.