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NCT02769039 · ClinicalTrials.gov registry record
Predictors of Motor Progression in Parkinson's Disease
A clinical trial, sponsored by University of Minnesota.
- Completed
- Registry status
- 72
- Enrollment target
NCT02769039 is a clinical trial that has completed, run by University of Minnesota. The registered enrollment target is 72 participants.
The verdict
NCT02769039 has completed, sponsored by University of Minnesota.
- COMPLETED
- Registry status
- 72 participants
- Enrollment target
Study Summary
Treatment resistant motor features, such as postural instability and freezing of gait are common in people with Parkinson's disease and major contributors to morbidity and mortality. This project will use sleep studies, quantitative motor assessments and magnetic resonance imaging to examine the relationship between abnormally increased muscle activity during rapid eye movement sleep and the development and progression of treatment-resistant postural instability and gait disturbances. Specifically, the investigators will test the hypothesis that anticipatory postural adjustments (weight and pressure shifts) during gait initiation are significantly reduced in people with Parkinson's disease who have abnormally elevated muscle activity during rapid eye movement (REM) sleep compared to individuals will Parkinson's disease whose REM sleep muscle activity is normal. In addition, the investigators will test the hypothesis that the level of RSWA at baseline is predictive of measures of motor decline (postural stability and gait) and alterations in the structure and function of locomotor brainstem networks. Since sleep disorders can emerge years before a diagnosis of Parkinson's disease, establishment of a link between sleep and treatment-resistant posture and gait disorders will help identify individuals at risk of developing these disabling motor features of disease.
Interventions
- OTHER No intervention. Observational studies of sleep, movement and brain imaging
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2015-10-01 |
| Est. Completion | 2019-05-31 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02769039
The ClinicalTrials.gov registry entry for NCT02769039 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 72 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Minnesota, which has 966 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which No intervention. Observational studies of sleep, movement and brain imaging is the first listed.
NCT02769039 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02769039 about?
NCT02769039 is a clinical study titled "Predictors of Motor Progression in Parkinson's Disease". Treatment resistant motor features, such as postural instability and freezing of gait are common in people with Parkinson's disease and major contributors to morbidity and mortality. This project will use sleep studies, quantitative motor assessments and magnetic resonance imaging to examine the rel...
What is the current status of trial NCT02769039?
This trial is currently completed. The enrollment target is 72 participants. The study started on 2015-10-01. Estimated completion is 2019-05-31.
What interventions are being tested in trial NCT02769039?
The interventions under investigation include: No intervention. Observational studies of sleep, movement and brain imaging (OTHER).
Who is sponsoring clinical trial NCT02769039?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
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