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NCT02768688 · ClinicalTrials.gov registry record · Early Phase 1
MRI of Glymphatic Clearance During Anesthetic Sedation
A Early Phase 1 study, sponsored by University of Pennsylvania.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 17
- Enrollment target
NCT02768688: Completed Early Phase 1 study, sponsored by University of Pennsylvania.
NCT02768688 is a Early Phase 1 study that has completed, run by University of Pennsylvania. The registered enrollment target is 17 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02768688, a Early Phase 1 study, has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 17 participants
- Enrollment target
Study Summary
This study is to assess the effect of dexmedetomidine anesthesia on glymphatic flow in 5 healthy human subjects as visualized by diffusion tensor MRI. The study is designed to measure clinically established, safe imaging of DTI and cerebral blood flow at baseline, during a continuous intravenous infusion of dexmedetomidine at doses designed to produce anesthesia-induced unconsciousness to simulate natural sleep, and again on return to wakefulness.
Interventions
- DRUG Dexmedetomidine
- OTHER Brain connectivity and physiology
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 17 participants |
| Start Date | 2014-07 |
| Est. Completion | 2017-12 |
| Phase | Early Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02768688
The ClinicalTrials.gov registry entry for NCT02768688 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 17 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Pennsylvania, which has 1,423 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Dexmedetomidine is the first listed.
NCT02768688 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02768688 about?
NCT02768688 is a clinical study titled "MRI of Glymphatic Clearance During Anesthetic Sedation". This study is to assess the effect of dexmedetomidine anesthesia on glymphatic flow in 5 healthy human subjects as visualized by diffusion tensor MRI. The study is designed to measure clinically established, safe imaging of DTI and cerebral blood flow at baseline, during a continuous intravenous inf...
What is the current status of trial NCT02768688?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 17 participants. The study started on 2014-07. Estimated completion is 2017-12.
What interventions are being tested in trial NCT02768688?
The interventions under investigation include: Dexmedetomidine (DRUG), Brain connectivity and physiology (OTHER).
Who is sponsoring clinical trial NCT02768688?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
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