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Pivotal Study of MRI-guided Transurethral Ultrasound Ablation in Patients With Localized Prostate Cancer
NCT02766543 · View on ClinicalTrials.gov ↗
Study Summary
A prospective, multi-center, single-arm study, planned in 150 patients. The primary objective of the study is to further evaluate the safety and efficacy of a magnetic resonance imaging (MRI)-guided transurethral ultrasound therapy system (TULSA-PRO) intended to ablate prostate tissue of patients with localized, organ-confined prostate cancer.
Conditions Studied
Interventions
- DEVICE MRI-guided Transurethral Ultrasound Ablation
Study Locations (14)
Other
- University Hospital of Cologne — Cologne
- Universitätsklinikum Heidelberg (University of Heidelberg, Dept of Urology) — Heidelberg
- Radboud University Medical Center — Nijmegen
- ResoFus Alomar (Hospital Universitari De Bellvitge) — Barcelona
Ontario
- London Health Sciences Centre — London
- Sunnybrook Health Sciences Centre — Toronto
California
- University of California Los Angeles — Los Angeles
Connecticut
- Yale Cancer Centre — New Haven
Illinois
- University of Chicago — Chicago
Indiana
- Indiana University — Indianapolis
Maryland
- Johns Hopkins Medicine — Baltimore
Michigan
- William Beaumont Hospital — Royal Oak
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2016-09-21 |
| Est. Completion | 2028-09-30 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02766543
The ClinicalTrials.gov registry entry for NCT02766543 describes a study currently listed as active not recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Profound Medical, which has 30 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Prostate Cancer appearing as the primary indexed condition, and to 1 intervention — of which MRI-guided Transurethral Ultrasound Ablation is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT02766543 reports 14 study locations spanning 10 distinct geographic areas — top geographies include Other, Ontario, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT02766543 about?
NCT02766543 is a clinical study titled "Pivotal Study of MRI-guided Transurethral Ultrasound Ablation in Patients With Localized Prostate Cancer". A prospective, multi-center, single-arm study, planned in 150 patients. The primary objective of the study is to further evaluate the safety and efficacy of a magnetic resonance imaging (MRI)-guided transurethral ultrasound therapy system (TULSA-PRO) intended to ablate prostate tissue of patients wi...
What is the current status of trial NCT02766543?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 150 participants. The study started on 2016-09-21. Estimated completion is 2028-09-30.
What conditions does trial NCT02766543 study?
This clinical trial studies the following conditions: Prostate Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT02766543?
The interventions under investigation include: MRI-guided Transurethral Ultrasound Ablation (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT02766543?
This trial is sponsored by Profound Medical, which has 30 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT02766543 being conducted?
This trial has 14 study locations across California, Connecticut, Illinois, Indiana, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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