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NCT02764437 · ClinicalTrials.gov registry record
AsthMatic Inflammation and Neurocircuitry Activation (MINA)
A clinical trial, sponsored by University of Wisconsin, Madison.
- Completed
- Registry status
- 43
- Enrollment target
NCT02764437: Completed study, sponsored by University of Wisconsin, Madison.
NCT02764437 is a clinical trial that has completed, run by University of Wisconsin, Madison. The registered enrollment target is 43 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02764437 has completed, sponsored by University of Wisconsin, Madison.
- COMPLETED
- Registry status
- 43 participants
- Enrollment target
Study Summary
The investigators have identified areas of the brain that are activated in response to disease-related emotional information, following whole lung allergen challenge in asthma. They propose that activity in these central nervous system locations, as measured by fMRI, is associated with the intensity of allergic inflammation, provoked by segmental bronchial challenge, in the absence of significant airflow obstruction. The investigators predict that this relationship will be mediated by changes in expression of genes in the IL-1β/IL-17 pathway.
Primary Outcome
The percent of eosinophils will be measured from the Bronchoalveolar lavage fluid pre segmental allergen challenge and will be measured 48 hours post segmental allergen challenge.
Interventions
- BIOLOGICAL Whole lung antigen challenge, segmental allergen challenge
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 43 participants |
| Start Date | 2016-07-28 |
| Est. Completion | 2020-03-31 |
What the finished NCT02764437 record still lists
NCT02764437 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 43 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Whole lung antigen challenge, segmental allergen challenge is the first listed.
NCT02764437 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02764437 about?
NCT02764437 is a clinical study titled "AsthMatic Inflammation and Neurocircuitry Activation (MINA)". The investigators have identified areas of the brain that are activated in response to disease-related emotional information, following whole lung allergen challenge in asthma. They propose that activity in these central nervous system locations, as measured by fMRI, is associated with the intensity...
What is the current status of trial NCT02764437?
This trial is currently completed. The enrollment target is 43 participants. The study started on 2016-07-28. Estimated completion is 2020-03-31.
What interventions are being tested in trial NCT02764437?
The interventions under investigation include: Whole lung antigen challenge, segmental allergen challenge (BIOLOGICAL).
Who is sponsoring clinical trial NCT02764437?
This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.
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