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NCT02762760 · ClinicalTrials.gov registry record · Phase 1

AP-011 Study to Evaluate the Safety of a Single Intra-articular Injection of Ampion™ for Arthritis of the Basal Thumb Joint

A Phase 1 study of Osteoarthritis of the Hand, sponsored by Ampio Pharmaceuticals..

Completed
Registry status
Phase 1
Development phase
15
Enrollment target
1
Study location

NCT02762760: Completed Phase 1 study of Osteoarthritis of the Hand, sponsored by Ampio Pharmaceuticals..

NCT02762760 is a Phase 1 study of Osteoarthritis of the Hand that has completed, run by Ampio Pharmaceuticals.. The registered enrollment target is 15 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02762760, a Phase 1 study of Osteoarthritis of the Hand, has completed, sponsored by Ampio Pharmaceuticals..

COMPLETED
Registry status
Phase 1
Development phase
15 participants
Enrollment target
1
Study location

Study Summary

This study will evaluate the safety of an intra-articular injection of AMPION™ in adults with pain due to osteoarthritis of the basal thumb joint.

Primary Outcome

The Clinical safety of treatment on base of the thumb will be assessed by recording AEs at all in-clinic visits and the 24-hour, post-injection telephone contact call, by the results of the physical examination of the thumb joint and vital signs (at all in-clinic visits), and by recording prior and concomitant medications including start/stop dates, indication, dose and frequency (at 24 hour post-injection telephone contact call and all in-clinic visits).

Conditions Studied

Interventions

  • BIOLOGICAL Saline
  • BIOLOGICAL AMPION™

Study Locations (1)

Colorado

  • Ampio Pharmaceuticals - Englewood

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2016-05
Est. Completion 2016-11
Phase Phase 1
Ampio Pharmaceuticals.

12 total trials

What the finished NCT02762760 record still lists

NCT02762760 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower).

The record links to 1 condition, with Osteoarthritis of the Hand appearing as the primary indexed condition, and to 2 interventions - of which Saline is the first listed.

NCT02762760 reports a single indexed study location in Colorado.

Frequently Asked Questions

What is clinical trial NCT02762760 about?

NCT02762760 is a clinical study titled "AP-011 Study to Evaluate the Safety of a Single Intra-articular Injection of Ampion™ for Arthritis of the Basal Thumb Joint". This study will evaluate the safety of an intra-articular injection of AMPION™ in adults with pain due to osteoarthritis of the basal thumb joint.

What is the current status of trial NCT02762760?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 15 participants. The study started on 2016-05. Estimated completion is 2016-11.

What conditions does trial NCT02762760 study?

This clinical trial studies the following conditions: Osteoarthritis of the Hand.

What interventions are being tested in trial NCT02762760?

The interventions under investigation include: Saline (BIOLOGICAL), AMPION™ (BIOLOGICAL).

Who is sponsoring clinical trial NCT02762760?

This trial is sponsored by Ampio Pharmaceuticals., which has 12 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02762760 being conducted?

This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

How this trial's enrollment target compares

Where NCT02762760's enrollment target sits among peer trials

15 1798th of 2000 higher than 157 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02762760, the US trial registry maintained by the National Library of Medicine. NCT02762760 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.