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NCT02761434 · ClinicalTrials.gov registry record · NA
The Effect of Vasopressin on Glucose Regulation
A NA study, sponsored by University of Arkansas, Fayetteville.
- Completed
- Registry status
- NA
- Development phase
- 60
- Enrollment target
NCT02761434: Completed NA study, sponsored by University of Arkansas, Fayetteville.
NCT02761434 is a NA study that has completed, run by University of Arkansas, Fayetteville. The registered enrollment target is 60 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02761434, a NA study, has completed, sponsored by University of Arkansas, Fayetteville.
- COMPLETED
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
Study Summary
Data from experimental animals and human epidemiological studies have suggested that hypohydration and/or low water intake is linked to poor glucose regulation and diabetes. The aim of this study is to investigate the effects of cellular dehydration on glucose in healthy non-diabetic individuals. METHODS: 60 males and females (30-55 y) will will undergo two experimental trials (ISO and HYP), consisting of a 2-h intravenous infusion of isotonic or hypertonic saline on two separate occasions, followed by a 4-h oral glucose tolerance test. Blood samples were taken from an antecubital vein in 30-min intervals starting at baseline for assessment of fluid and glucose regulating factors. Thirst will be assessed via visual analog following each blood sample. Energy substrate oxidation will be calculated via indirect calorimetry every 60 min.
Primary Outcome
the area under the glucose curve (AUC) in mg/dL x min
Interventions
- OTHER Hypertonic Saline (3% NaCl)
- OTHER Isotonic Saline (0.9% NaCl)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2016-04-13 |
| Est. Completion | 2017-05-15 |
| Phase | NA |
What the finished NCT02761434 record still lists
NCT02761434 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which Hypertonic Saline (3% NaCl) is the first listed.
NCT02761434 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02761434 about?
NCT02761434 is a clinical study titled "The Effect of Vasopressin on Glucose Regulation". Data from experimental animals and human epidemiological studies have suggested that hypohydration and/or low water intake is linked to poor glucose regulation and diabetes. The aim of this study is to investigate the effects of cellular dehydration on glucose in healthy non-diabetic individuals. ME...
What is the current status of trial NCT02761434?
This trial is currently completed. It is a NA study. The enrollment target is 60 participants. The study started on 2016-04-13. Estimated completion is 2017-05-15.
What interventions are being tested in trial NCT02761434?
The interventions under investigation include: Hypertonic Saline (3% NaCl) (OTHER), Isotonic Saline (0.9% NaCl) (OTHER).
Who is sponsoring clinical trial NCT02761434?
This trial is sponsored by University of Arkansas, Fayetteville, which has 25 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02761434's enrollment target sits among peer trials
60 1164th of 2000 higher than 745 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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