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NCT02759887 · ClinicalTrials.gov registry record · NA
Relationship Between Down Syndrome (DS) and Alzheimer's Disease (AD)
A NA study of Down Syndrome and Alzheimer's Dementia, sponsored by St. Joseph's Hospital and Medical Center, Phoenix.
- Completed
- Registry status
- NA
- Development phase
- 19
- Enrollment target
- 1
- Study location
NCT02759887 is a NA study of Down Syndrome and Alzheimer's Dementia that has completed, run by St. Joseph's Hospital and Medical Center, Phoenix. The registered enrollment target is 19 participants, below the 2,471-participant average among 54 other Down Syndrome trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.
The verdict
NCT02759887, a NA study of Down Syndrome and Alzheimer's Dementia, has completed, sponsored by St. Joseph's Hospital and Medical Center, Phoenix.
- COMPLETED
- Registry status
- NA
- Development phase
- 19 participants
- Enrollment target
- 1
- Study location
Study Summary
In order to treat individuals with Down syndrome (DS) better and more efficiently and to gain more insights on its relation to Alzheimer's disease (AD), a comprehensive understanding is needed for its progression in the early or preclinical phase using various biomarkers. DS is a significant risk factor for the early development of AD, with plaques and tangles typically developing by age 35. A better understanding is needed of early markers of the disease in DS patients. Additionally the DS population represents a unique group - due to this elevated risk for AD - to examine biomarkers that may translate in general outside of the DS population to individuals at risk for developing late onset AD. In this proposal, the researchers will assess the longitudinal changes of various biomarkers in a cohort of individuals similar in design to the cross-sectional sectional study in the preliminary data.
Conditions Studied
Interventions
- PROCEDURE MRI
- PROCEDURE biospecimen collection
- OTHER cognitive assessments
- OTHER caregiver questionnaire
- PROCEDURE Florbetapir F18 imaging
Study Locations (1)
Arizona
- St. Joseph's Hospital and Medical Center - Phoenix
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2016-11 |
| Est. Completion | 2018-12 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02759887
The ClinicalTrials.gov registry entry for NCT02759887 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 19 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,471-participant average among 54 other Down Syndrome trials with a reported enrollment target (99% lower). The listed sponsor is St. Joseph's Hospital and Medical Center, Phoenix, which has 44 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Down Syndrome appearing as the primary indexed condition, and to 5 interventions - of which MRI is the first listed.
NCT02759887 reports 1 study location spanning 1 distinct geographic area - top geographies include Arizona.
Frequently Asked Questions
What is clinical trial NCT02759887 about?
NCT02759887 is a clinical study titled "Relationship Between Down Syndrome (DS) and Alzheimer's Disease (AD)". In order to treat individuals with Down syndrome (DS) better and more efficiently and to gain more insights on its relation to Alzheimer's disease (AD), a comprehensive understanding is needed for its progression in the early or preclinical phase using various biomarkers. DS is a significant risk fa...
What is the current status of trial NCT02759887?
This trial is currently completed. It is a NA study. The enrollment target is 19 participants. The study started on 2016-11. Estimated completion is 2018-12.
What conditions does trial NCT02759887 study?
This clinical trial studies the following conditions: Down Syndrome, Alzheimer's Dementia.
What interventions are being tested in trial NCT02759887?
The interventions under investigation include: MRI (PROCEDURE), biospecimen collection (PROCEDURE), cognitive assessments (OTHER), caregiver questionnaire (OTHER), Florbetapir F18 imaging (PROCEDURE).
Who is sponsoring clinical trial NCT02759887?
This trial is sponsored by St. Joseph's Hospital and Medical Center, Phoenix, which has 44 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02759887 being conducted?
This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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