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NCT02757521 · ClinicalTrials.gov registry record · Early Phase 1
Nitrous TRD Bipolar Depression
A Early Phase 1 study, sponsored by Washington University School of Medicine.
- Terminated
- Registry status
- Early Phase 1
- Development phase
- 1
- Enrollment target
NCT02757521: Clinical Trial Early Phase 1 study, sponsored by Washington University School of Medicine.
NCT02757521 is a Early Phase 1 study that was terminated before completion, run by Washington University School of Medicine. The registered enrollment target is 1 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02757521, a Early Phase 1 study, was terminated before completion, sponsored by Washington University School of Medicine.
- TERMINATED
- Registry status
- Early Phase 1
- Development phase
- 1 participants
- Enrollment target
Study Summary
Investigators will study approximately 64 patients with Treatment-Resistant Bipolar Depressive Disorder, defined as a failure of at least 1 antidepressants in the current depressive episode and 2 lifetime medication failures. The study will last approximately 6 to 8 weeks, involving randomization into one of two treatment groups receiving 3 one hour long inhalation treatments over a week.
Primary Outcome
Change in depressive symptoms on MADRS scale between baseline and day 7 follow up
Interventions
- DRUG Placebo
- DRUG Nitrous Oxide
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1 participants |
| Start Date | 2016-03-25 |
| Est. Completion | 2016-12-06 |
| Phase | Early Phase 1 |
Why NCT02757521 stopped before completion
NCT02757521 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT02757521 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02757521 about?
NCT02757521 is a clinical study titled "Nitrous TRD Bipolar Depression". Investigators will study approximately 64 patients with Treatment-Resistant Bipolar Depressive Disorder, defined as a failure of at least 1 antidepressants in the current depressive episode and 2 lifetime medication failures. The study will last approximately 6 to 8 weeks, involving randomization in...
What is the current status of trial NCT02757521?
This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 1 participants. The study started on 2016-03-25. Estimated completion is 2016-12-06.
What interventions are being tested in trial NCT02757521?
The interventions under investigation include: Placebo (DRUG), Nitrous Oxide (DRUG).
Who is sponsoring clinical trial NCT02757521?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02757521's enrollment target sits among peer trials
1 1985th of 2000 the lowest of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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