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NCT02754518 · ClinicalTrials.gov registry record · Phase 4

Demonstration of Reverse Remodeling Effects of Entresto. Using Echocardiography Endocardial Surface Analysis

A Phase 4 study, sponsored by University of Chicago.

Completed
Registry status
Phase 4
Development phase
40
Enrollment target

NCT02754518: Completed Phase 4 study, sponsored by University of Chicago.

NCT02754518 is a Phase 4 study that has completed, run by University of Chicago. The registered enrollment target is 40 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02754518, a Phase 4 study, has completed, sponsored by University of Chicago.

COMPLETED
Registry status
Phase 4
Development phase
40 participants
Enrollment target

Study Summary

This study intends to measure the effects of valsartan/sacubitril compared to baseline standard medical heart failure therapy on reverse remodeling using echocardiographic endocardial surface analysis techniques to assess changes in ventricular volume, function, and shape.

Primary Outcome

LV Remodeling 2D End-Diastolic Diameter (cm)

Interventions

  • DRUG Entresto

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2016-04
Est. Completion 2019-04
Phase Phase 4
University of Chicago

796 total trials

What the finished NCT02754518 record still lists

NCT02754518 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower).

The record links to 0 conditions, and to 1 intervention - of which Entresto is the first listed.

NCT02754518 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02754518 about?

NCT02754518 is a clinical study titled "Demonstration of Reverse Remodeling Effects of Entresto. Using Echocardiography Endocardial Surface Analysis". This study intends to measure the effects of valsartan/sacubitril compared to baseline standard medical heart failure therapy on reverse remodeling using echocardiographic endocardial surface analysis techniques to assess changes in ventricular volume, function, and shape.

What is the current status of trial NCT02754518?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 40 participants. The study started on 2016-04. Estimated completion is 2019-04.

What interventions are being tested in trial NCT02754518?

The interventions under investigation include: Entresto (DRUG).

Who is sponsoring clinical trial NCT02754518?

This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02754518's enrollment target sits among peer trials

40 1397th of 2000 higher than 533 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02754518, the US trial registry maintained by the National Library of Medicine. NCT02754518 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.