Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02751528 · ClinicalTrials.gov registry record · Phase 1

QUILT-3.013: Study of Ad5 [E1-, E2b-]-HER2/Neu Vaccine (ETBX-021) in Subjects With Unresectable Locally Advanced or Metastatic HER2-Expressing Breast Cancer

A Phase 1 study, sponsored by NantBioScience.

Terminated
Registry status
Phase 1
Development phase
3
Enrollment target

NCT02751528: Clinical Trial Phase 1 study, sponsored by NantBioScience.

NCT02751528 is a Phase 1 study that was terminated before completion, run by NantBioScience. The registered enrollment target is 3 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT02751528, a Phase 1 study, was terminated before completion, sponsored by NantBioScience.

TERMINATED
Registry status
Phase 1
Development phase
3 participants
Enrollment target

Study Summary

The purpose of this study is to determine whether ETBX-021 is safe and effective in the treatment of unresectable locally advanced or metastatic HER2-low-expressing breast cancer.

Interventions

  • BIOLOGICAL ETBX-021

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 2017-03-04
Est. Completion 2018-08-16
Phase Phase 1
NantBioScience

3 total trials

Why NCT02751528 stopped before completion

NCT02751528 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 1 intervention - of which ETBX-021 is the first listed.

NCT02751528 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02751528 about?

NCT02751528 is a clinical study titled "QUILT-3.013: Study of Ad5 [E1-, E2b-]-HER2/Neu Vaccine (ETBX-021) in Subjects With Unresectable Locally Advanced or Metastatic HER2-Expressing Breast Cancer". The purpose of this study is to determine whether ETBX-021 is safe and effective in the treatment of unresectable locally advanced or metastatic HER2-low-expressing breast cancer.

What is the current status of trial NCT02751528?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 3 participants. The study started on 2017-03-04. Estimated completion is 2018-08-16.

What interventions are being tested in trial NCT02751528?

The interventions under investigation include: ETBX-021 (BIOLOGICAL).

Who is sponsoring clinical trial NCT02751528?

This trial is sponsored by NantBioScience, which has 3 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02751528's enrollment target sits among peer trials

3 1999th of 2000 higher than 1 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT02751528, the US trial registry maintained by the National Library of Medicine. NCT02751528 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.