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NCT02741115 · ClinicalTrials.gov registry record · Phase 3

Fontan Udenafil Exercise Longitudinal Assessment Trial

A Phase 3 study of Single Ventricle Heart Disease, sponsored by Mezzion Pharma Co..

Completed
Registry status
Phase 3
Development phase
400
Enrollment target
20
Study locations

NCT02741115 is a Phase 3 study of Single Ventricle Heart Disease that has completed, run by Mezzion Pharma Co.. The registered enrollment target is 400 participants, above the 125-participant average among 4 other Single Ventricle Heart Disease trials with a reported enrollment target (220% higher). The trial reports 20 study locations across 16 states.

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The verdict

NCT02741115, a Phase 3 study of Single Ventricle Heart Disease, has completed, sponsored by Mezzion Pharma Co..

COMPLETED
Registry status
Phase 3
Development phase
400 participants
Enrollment target
20
Study locations

Study Summary

This study will evaluate the clinical efficacy and safety of udenafil, an orally administered, potent and selective inhibitor of PDE5, versus placebo for the treatment of adolescent subjects who have undergone the Fontan procedure.

Interventions

  • DRUG Placebo
  • DRUG Udenafil

Study Locations (20)

California

  • Children's Hospital Los Angeles - Los Angeles
  • Cedars/Sinai Heart Institute - Los Angeles
  • Rady Children's Hospital - San Diego

Missouri

  • Children's Mercy Hospital Kansas City - Kansas City
  • Washington University St. Louis/St.Louis Children's Hospital - St Louis

Ohio

  • Cincinnati Children's Hospital Medical Center - Cincinnati
  • Nationwide Children's Hosptial - Columbus

Arizona

  • Phoenix Children's Hospital/Children's Heart Center at Phoenix Children's Hospital - Phoenix

Colorado

  • Children's Hospital Colorado - Aurora

Delaware

  • Nemours Cardiac Center/Alfred I. duPont Hospital for Children - Wilmington

District of Columbia

  • Children's National Medical Center - Washington D.C.

Florida

  • Johns Hopkins All Children's Heart Institute - St. Petersburg

Trial Details

FieldValue
Enrollment Target 400 participants
Start Date 2016-07-22
Est. Completion 2019-04-30
Phase Phase 3

Sponsor

Mezzion Pharma Co.

5 total trials

What the Registry Record Tells You About NCT02741115

The ClinicalTrials.gov registry entry for NCT02741115 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 400 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 125-participant average among 4 other Single Ventricle Heart Disease trials with a reported enrollment target (220% higher). The listed sponsor is Mezzion Pharma Co., which has 5 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Single Ventricle Heart Disease appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT02741115 reports 20 study locations spanning 16 distinct geographic areas - top geographies include California, Missouri, Ohio.

Frequently Asked Questions

What is clinical trial NCT02741115 about?

NCT02741115 is a clinical study titled "Fontan Udenafil Exercise Longitudinal Assessment Trial". This study will evaluate the clinical efficacy and safety of udenafil, an orally administered, potent and selective inhibitor of PDE5, versus placebo for the treatment of adolescent subjects who have undergone the Fontan procedure.

What is the current status of trial NCT02741115?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 400 participants. The study started on 2016-07-22. Estimated completion is 2019-04-30.

What conditions does trial NCT02741115 study?

This clinical trial studies the following conditions: Single Ventricle Heart Disease.

What interventions are being tested in trial NCT02741115?

The interventions under investigation include: Placebo (DRUG), Udenafil (DRUG).

Who is sponsoring clinical trial NCT02741115?

This trial is sponsored by Mezzion Pharma Co., which has 5 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02741115 being conducted?

This trial has 20 study locations across Arizona, California, Colorado, Delaware, District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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