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NCT02738450 · ClinicalTrials.gov registry record · Phase 1

Safety, Tolerability and Immunogenicity of ACI-24 Vaccine in Adults With Down Syndrome

A Phase 1 study of Down Syndrome, sponsored by AC Immune.

Completed
Registry status
Phase 1
Development phase
20
Enrollment target
4
Study locations

NCT02738450 is a Phase 1 study of Down Syndrome that has completed, run by AC Immune. The registered enrollment target is 20 participants, below the 2,471-participant average among 54 other Down Syndrome trials with a reported enrollment target (99% lower). The trial reports 4 study locations across 4 states.

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The verdict

NCT02738450, a Phase 1 study of Down Syndrome, has completed, sponsored by AC Immune.

COMPLETED
Registry status
Phase 1
Development phase
20 participants
Enrollment target
4
Study locations

Study Summary

The purpose of this study is to test in adults with Down Syndrome the safety, tolerability and immunogenicity of a vaccine, ACI-24.

Conditions Studied

Down Syndrome

Interventions

  • BIOLOGICAL Placebo
  • BIOLOGICAL ACI-24 low dose
  • BIOLOGICAL ACI-24 high dose

Study Locations (4)

Arizona

  • St. Joseph's Hospital and Medical Center - Barrow Neurology Clinics - Phoenix

California

  • UCSD Adult Down Syndrome Program - La Jolla

Maryland

  • Johns Hopkins University - Baltimore

Massachusetts

  • Massachusetts General Hospital - Boston

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2016-03
Est. Completion 2020-06
Phase Phase 1

Sponsor

AC Immune

2 total trials

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What the Registry Record Tells You About NCT02738450

The ClinicalTrials.gov registry entry for NCT02738450 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,471-participant average among 54 other Down Syndrome trials with a reported enrollment target (99% lower). The listed sponsor is AC Immune, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Down Syndrome appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.

NCT02738450 reports 4 study locations spanning 4 distinct geographic areas - top geographies include Arizona, California, Maryland.

Frequently Asked Questions

What is clinical trial NCT02738450 about?

NCT02738450 is a clinical study titled "Safety, Tolerability and Immunogenicity of ACI-24 Vaccine in Adults With Down Syndrome". The purpose of this study is to test in adults with Down Syndrome the safety, tolerability and immunogenicity of a vaccine, ACI-24.

What is the current status of trial NCT02738450?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2016-03. Estimated completion is 2020-06.

What conditions does trial NCT02738450 study?

This clinical trial studies the following conditions: Down Syndrome.

What interventions are being tested in trial NCT02738450?

The interventions under investigation include: Placebo (BIOLOGICAL), ACI-24 low dose (BIOLOGICAL), ACI-24 high dose (BIOLOGICAL).

Who is sponsoring clinical trial NCT02738450?

This trial is sponsored by AC Immune, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02738450 being conducted?

This trial has 4 study locations across Arizona, California, Maryland, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.