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NCT02738281 · ClinicalTrials.gov registry record
Natural History of Rett Syndrome & Related Disorders
A clinical trial, sponsored by University of Alabama at Birmingham.
- Completed
- Registry status
- 1,044
- Enrollment target
NCT02738281: Completed study, sponsored by University of Alabama at Birmingham.
NCT02738281 is a clinical trial that has completed, run by University of Alabama at Birmingham. The registered enrollment target is 1,044 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02738281 has completed, sponsored by University of Alabama at Birmingham.
- COMPLETED
- Registry status
- 1,044 participants
- Enrollment target
Study Summary
The purpose of this study is to advance understanding of the natural history of Rett syndrome (RTT), MECP2-duplication disorder (MECP2 Dup), CDKL5, FOXG1, and individuals with MECP2 mutations who do not have RTT including the range of clinical involvement and to correlate genotype-phenotype over a broad spectrum of phenotypes. While much has been learned about RTT, improvements are required in understanding the role of factors such as X chromosome inactivation, genetic background, and others including the environment, on the great variability observed even between individuals with the same MECP2 mutation. These data will be essential to the development and conduct of clinical trials that are anticipated from ongoing studies in animal models for RTT. This study will not include clinical trials, but should set the stage for such trials and other translational research projects (e.g., development of biomarkers).
Primary Outcome
subject's height will be measured in inches at baseline and at 5 years. The change will be calculated and then the mean change will be reported.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,044 participants |
| Start Date | 2015-11 |
| Est. Completion | 2021-07-31 |
What the finished NCT02738281 record still lists
NCT02738281 is an observational study that tracks outcomes without assigning an intervention. Its 1,044 participants enrollment target places it among the larger protocols in the corpus.
The record links to 0 conditions, and to 0 interventions.
NCT02738281 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02738281 about?
NCT02738281 is a clinical study titled "Natural History of Rett Syndrome & Related Disorders". The purpose of this study is to advance understanding of the natural history of Rett syndrome (RTT), MECP2-duplication disorder (MECP2 Dup), CDKL5, FOXG1, and individuals with MECP2 mutations who do not have RTT including the range of clinical involvement and to correlate genotype-phenotype over a b...
What is the current status of trial NCT02738281?
This trial is currently completed. The enrollment target is 1,044 participants. The study started on 2015-11. Estimated completion is 2021-07-31.
Who is sponsoring clinical trial NCT02738281?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
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