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NCT02737436 · ClinicalTrials.gov registry record · NA
Intranasal Oxytocin and Maternal Neglect
A NA study of Maternal Behavior, sponsored by Baylor College of Medicine.
- Completed
- Registry status
- NA
- Development phase
- 132
- Enrollment target
- 2
- Study locations
NCT02737436: Completed NA study of Maternal Behavior, sponsored by Baylor College of Medicine.
NCT02737436 is a NA study of Maternal Behavior that has completed, run by Baylor College of Medicine. The registered enrollment target is 132 participants, below the 580-participant average among 13 other Maternal Behavior trials with a reported enrollment target (77% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02737436, a NA study of Maternal Behavior, has completed, sponsored by Baylor College of Medicine.
- COMPLETED
- Registry status
- NA
- Development phase
- 132 participants
- Enrollment target
- 2
- Study locations
Study Summary
The investigators plan to conduct functional MRI scanning with a group of mothers who are blindly and randomly assigned either intranasal oxytocin or a placebo. The purpose of this investigation is to explore how oxytocin may modify early maternal brain and behavioral responses to infant cues. This study will examine, for the first time, a potential pharmacological intervention for maternal neglect which targets core neurobiological deficits. This may eventually be used to supplement and augment other psychosocial and behavioral interventions. In addition, the investigators will examine sex differences in parental brain and behavioral responses to oxytocin by also recruiting fathers to participate in a similar protocol.
Primary Outcome
We will compare the BOLD signal of regions in the brain (including the ventral striatum, caudate, putamen, amygdala, and the medial prefrontal cortex) in mothers who receive intranasal oxytocin, compared to placebo. In every analysis, we measure the difference in brain response (BOLD signal) between viewing the mother's own infant (O) more than unknown infant (U) faces (O\>U), during fMRI scanning.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Intranasal Oxytocin
- PROCEDURE Functional MRI scanning
Study Locations (2)
Iowa
- University of Iowa - Iowa City
Texas
- Children's Nutrition Research Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 132 participants |
| Start Date | 2010-05 |
| Est. Completion | 2019-03 |
| Phase | NA |
What the finished NCT02737436 record still lists
NCT02737436 is an interventional study that assigns participants to a tested intervention. The registered 132 participants enrollment target is mid-sized for trials with a published cap, below the 580-participant average among 13 other Maternal Behavior trials with a reported enrollment target (77% lower).
The record links to 1 condition, with Maternal Behavior appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT02737436 reports a single indexed study location in Iowa, Texas.
Frequently Asked Questions
What is clinical trial NCT02737436 about?
NCT02737436 is a clinical study titled "Intranasal Oxytocin and Maternal Neglect". The investigators plan to conduct functional MRI scanning with a group of mothers who are blindly and randomly assigned either intranasal oxytocin or a placebo. The purpose of this investigation is to explore how oxytocin may modify early maternal brain and behavioral responses to infant cues. This ...
What is the current status of trial NCT02737436?
This trial is currently completed. It is a NA study. The enrollment target is 132 participants. The study started on 2010-05. Estimated completion is 2019-03.
What conditions does trial NCT02737436 study?
This clinical trial studies the following conditions: Maternal Behavior.
What interventions are being tested in trial NCT02737436?
The interventions under investigation include: Placebo (DRUG), Intranasal Oxytocin (DRUG), Functional MRI scanning (PROCEDURE).
Who is sponsoring clinical trial NCT02737436?
This trial is sponsored by Baylor College of Medicine, which has 616 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02737436 being conducted?
This trial has 2 study locations across Iowa, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Maternal Behavior
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02737436's enrollment target sits among peer trials
132 6th of 13 higher than 8 of 13 other Maternal Behavior trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Maternal Behavior trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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