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NCT02730988 · ClinicalTrials.gov registry record · NA
Effect of High Protein Weight Loss for Seniors
A NA study, sponsored by Wake Forest University.
- Completed
- Registry status
- NA
- Development phase
- 96
- Enrollment target
NCT02730988 is a NA study that has completed, run by Wake Forest University. The registered enrollment target is 96 participants.
The verdict
NCT02730988, a NA study, has completed, sponsored by Wake Forest University.
- COMPLETED
- Registry status
- NA
- Development phase
- 96 participants
- Enrollment target
Study Summary
Intentional weight loss in obese, older adults remains controversial. Although caloric restriction, resulting in significant weight and fat mass loss, ameliorates many clinical consequences of obesity, recommendation of intentional weight loss in aging remains controversial. Reluctance stems, at least in part, from loss of lean and bone mass known to accompany overall weight loss and potential exacerbation of age-related risk of disability and fracture. Accordingly, current treatment guidelines call fhttp://google.wfu.edu/or weight-loss therapy that minimizes muscle and bone losses for older persons who are obese and who have functional impairments or medical complications that can benefit from weight loss. Amount of dietary protein consumed during caloric restriction may be a key determinant in maintaining fat-free mass during weight loss. Adequate dietary protein is essential for skeletal muscle anabolism; and, epidemiological evidence in older adults point to a salutary effect of protein intake above the current RDA (0.8 g/kg/day) on body composition. Indeed, a recent position statement by the PRO-TAGE study group advises consumption of 1.0-1.2 g/kg/d in older adults during weight-stable conditions to aid in the maintenance of lean body mass and function. Practical achievement of this level of protein intake is often difficult for obese, older adults undergoing weight loss, yet may be critical to offset weight loss-associated lean mass loss. Preliminary data from our group show a lean mass sparing effect of high protein consumption during caloric restriction. In post-menopausal women undergoing a 5-month intentional weight loss program, consumption of a high (1.2 g/kg/day) versus low (0.6 g/kg/day) protein diet was associated with 50% attenuation (17% vs. 37%) of lean mass loss. While promising, results have yet to be translated to functional changes in a tightly controlled trial of weight loss in obese, older adults. The primary goal of this study is to determ
Interventions
- BEHAVIORAL Weight Stable Group
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 96 participants |
| Start Date | 2015-07-01 |
| Est. Completion | 2017-04-17 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02730988
The ClinicalTrials.gov registry entry for NCT02730988 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 96 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Wake Forest University, which has 100 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Weight Stable Group is the first listed.
NCT02730988 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02730988 about?
NCT02730988 is a clinical study titled "Effect of High Protein Weight Loss for Seniors". Intentional weight loss in obese, older adults remains controversial. Although caloric restriction, resulting in significant weight and fat mass loss, ameliorates many clinical consequences of obesity, recommendation of intentional weight loss in aging remains controversial. Reluctance stems, at lea...
What is the current status of trial NCT02730988?
This trial is currently completed. It is a NA study. The enrollment target is 96 participants. The study started on 2015-07-01. Estimated completion is 2017-04-17.
What interventions are being tested in trial NCT02730988?
The interventions under investigation include: Weight Stable Group (BEHAVIORAL).
Who is sponsoring clinical trial NCT02730988?
This trial is sponsored by Wake Forest University, which has 100 total clinical trials registered on ClinicalTrials.gov.
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