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NCT02726750 · ClinicalTrials.gov registry record

Observational Prospective Research Study In Monoclonal Gammopathies leadINg to Myeloma

A clinical trial of Monoclonal Gammopathy of Undetermined Significance and Smoldering Plasma Cell Myeloma, sponsored by M.D. Anderson Cancer Center.

Recruiting
Registry status
200
Enrollment target
1
Study location

NCT02726750: Recruiting study of Monoclonal Gammopathy of Undetermined Significance and Smoldering Plasma Cell Myeloma, sponsored by M.D. Anderson Cancer Center.

NCT02726750 is a study of Monoclonal Gammopathy of Undetermined Significance and Smoldering Plasma Cell Myeloma that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 200 participants, below the 662-participant average among 11 other Monoclonal Gammopathy of Undetermined Significance trials with a reported enrollment target (70% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02726750, a study of Monoclonal Gammopathy of Undetermined Significance and Smoldering Plasma Cell Myeloma, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.

RECRUITING
Registry status
200 participants
Enrollment target
1
Study location

Study Summary

The goal of this study is to find markers that may help to predict why some patients who have monoclonal gammopathy of unknown significance (MGUS) or smoldering multiple myeloma (SMM) that have no signs or symptoms of disease (asymptomatic) develop multiple myeloma, while others do not. Studying markers such as age, level of proteins in blood, percent of abnormal blood cells in the bone marrow, genes in the abnormal blood cells, and bone abnormalities may help researchers to validate clinical and genomic predictors for future use in clinical practice.

Primary Outcome

Kaplan-Meier method will be used to estimate time to MM progression. Log-rank test will be used to evaluate the difference in rate of progression between/among patient groups.

Interventions

  • PROCEDURE Biospecimen Collection
  • OTHER Laboratory Biomarker Analysis

Study Locations (1)

Texas

  • M D Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2015-12-14
Est. Completion 2026-04-30
M.D. Anderson Cancer Center

2,692 total trials

What NCT02726750 shows while recruiting

NCT02726750 is an observational study that tracks outcomes without assigning an intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, below the 662-participant average among 11 other Monoclonal Gammopathy of Undetermined Significance trials with a reported enrollment target (70% lower).

The record links to 2 conditions, with Monoclonal Gammopathy of Undetermined Significance appearing as the primary indexed condition, and to 2 interventions - of which Biospecimen Collection is the first listed.

NCT02726750 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT02726750 about?

NCT02726750 is a clinical study titled "Observational Prospective Research Study In Monoclonal Gammopathies leadINg to Myeloma". The goal of this study is to find markers that may help to predict why some patients who have monoclonal gammopathy of unknown significance (MGUS) or smoldering multiple myeloma (SMM) that have no signs or symptoms of disease (asymptomatic) develop multiple myeloma, while others do not. Studying mar...

What is the current status of trial NCT02726750?

This trial is currently recruiting. The enrollment target is 200 participants. The study started on 2015-12-14. Estimated completion is 2026-04-30.

What conditions does trial NCT02726750 study?

This clinical trial studies the following conditions: Monoclonal Gammopathy of Undetermined Significance, Smoldering Plasma Cell Myeloma.

What interventions are being tested in trial NCT02726750?

The interventions under investigation include: Biospecimen Collection (PROCEDURE), Laboratory Biomarker Analysis (OTHER).

Who is sponsoring clinical trial NCT02726750?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02726750 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Monoclonal Gammopathy of Undetermined Significance

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02726750's enrollment target sits among peer trials

200 5th of 11 higher than 5 of 11 other Monoclonal Gammopathy of Undetermined Significance trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Monoclonal Gammopathy of Undetermined Significance trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02726750, the US trial registry maintained by the National Library of Medicine. NCT02726750 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.