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NCT02716038 · ClinicalTrials.gov registry record · Phase 2
Neoadjuvant MPDL3280A, Nab-paclitaxel and Carboplatin (MAC) in NSCLC
A Phase 2 study, sponsored by Columbia University.
- Completed
- Registry status
- Phase 2
- Development phase
- 39
- Enrollment target
NCT02716038: Completed Phase 2 study, sponsored by Columbia University.
NCT02716038 is a Phase 2 study that has completed, run by Columbia University. The registered enrollment target is 39 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (71% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02716038, a Phase 2 study, has completed, sponsored by Columbia University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 39 participants
- Enrollment target
Study Summary
This is a research study to test the effectiveness of nab-paclitaxel + carboplatin + MPDL3280A for treatment of non-small-cell lung carcinoma (NSCLC), which is a type of lung cancer. The study aims to determine if chemotherapy combined with immune-based therapy can lead to improvement in tumor response rates over historical response rates with chemotherapy alone.
Primary Outcome
Major pathologic response rate (MPR) is defined as \> or = 90% decrease in viable tumor.
Interventions
- DRUG Carboplatin
- DRUG Nab-paclitaxel
- DRUG MPDL3280A
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 39 participants |
| Start Date | 2016-06-07 |
| Est. Completion | 2022-10-01 |
| Phase | Phase 2 |
What the finished NCT02716038 record still lists
NCT02716038 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 39 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (71% lower).
The record links to 0 conditions, and to 3 interventions - of which Carboplatin is the first listed.
NCT02716038 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02716038 about?
NCT02716038 is a clinical study titled "Neoadjuvant MPDL3280A, Nab-paclitaxel and Carboplatin (MAC) in NSCLC". This is a research study to test the effectiveness of nab-paclitaxel + carboplatin + MPDL3280A for treatment of non-small-cell lung carcinoma (NSCLC), which is a type of lung cancer. The study aims to determine if chemotherapy combined with immune-based therapy can lead to improvement in tumor respo...
What is the current status of trial NCT02716038?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 39 participants. The study started on 2016-06-07. Estimated completion is 2022-10-01.
What interventions are being tested in trial NCT02716038?
The interventions under investigation include: Carboplatin (DRUG), Nab-paclitaxel (DRUG), MPDL3280A (DRUG).
Who is sponsoring clinical trial NCT02716038?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02716038's enrollment target sits among peer trials
39 1459th of 2000 higher than 534 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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