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NCT02709655 · ClinicalTrials.gov registry record · Phase 3

Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Participants Aged 7 to 11 Years With Major Depressive Disorder (MDD)

A Phase 3 study, sponsored by H. Lundbeck A/S.

Completed
Registry status
Phase 3
Development phase
683
Enrollment target

NCT02709655: Completed Phase 3 study, sponsored by H. Lundbeck A/S.

NCT02709655 is a Phase 3 study that has completed, run by H. Lundbeck A/S. The registered enrollment target is 683 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (12% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02709655, a Phase 3 study, has completed, sponsored by H. Lundbeck A/S.

COMPLETED
Registry status
Phase 3
Development phase
683 participants
Enrollment target

Study Summary

Investigation of the efficacy and safety of a new potential treatment of Major depressive disorder (MDD) in paediatric participants (age 7 to 11 years).

Primary Outcome

The CDRS-R is a clinician-rated scale to measure the severity of depression in children and adolescents. The CDRS-R was rated by a clinician following interviews with the child and parent and consisted of 17 items out of which 3 items rated nonverbal observations (listless speech, hypoactivity, and depressed affect). Fourteen items were rated on a 7-point scale from 1 to 7, and 3 items (sleep disturbance, appetite disturbance, and listless speech) were scored on a 5-point scale from 1 to 5. A ra

Interventions

  • OTHER Placebo
  • DRUG Vortioxetine 10 mg/day
  • DRUG Vortioxetine 20 mg/day
  • DRUG Fluoxetine 20mg/day

Trial Details

FieldValue
Enrollment Target 683 participants
Start Date 2016-05-18
Est. Completion 2022-01-21
Phase Phase 3
H. Lundbeck A/S

72 total trials

What the finished NCT02709655 record still lists

NCT02709655 is an interventional study that assigns participants to a tested intervention. The registered 683 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (12% lower).

The record links to 0 conditions, and to 4 interventions - of which Placebo is the first listed.

NCT02709655 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02709655 about?

NCT02709655 is a clinical study titled "Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Participants Aged 7 to 11 Years With Major Depressive Disorder (MDD)". Investigation of the efficacy and safety of a new potential treatment of Major depressive disorder (MDD) in paediatric participants (age 7 to 11 years).

What is the current status of trial NCT02709655?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 683 participants. The study started on 2016-05-18. Estimated completion is 2022-01-21.

What interventions are being tested in trial NCT02709655?

The interventions under investigation include: Placebo (OTHER), Vortioxetine 10 mg/day (DRUG), Vortioxetine 20 mg/day (DRUG), Fluoxetine 20mg/day (DRUG).

Who is sponsoring clinical trial NCT02709655?

This trial is sponsored by H. Lundbeck A/S, which has 72 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02709655's enrollment target sits among peer trials

683 529th of 2000 higher than 1,472 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02709655, the US trial registry maintained by the National Library of Medicine. NCT02709655 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.