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NCT02709018 · ClinicalTrials.gov registry record · NA
A Controlled Trial of Losartan in Posttraumatic Stress Disorder
A NA study, sponsored by University of California, San Diego.
- Completed
- Registry status
- NA
- Development phase
- 149
- Enrollment target
NCT02709018 is a NA study that has completed, run by University of California, San Diego. The registered enrollment target is 149 participants.
The verdict
NCT02709018, a NA study, has completed, sponsored by University of California, San Diego.
- COMPLETED
- Registry status
- NA
- Development phase
- 149 participants
- Enrollment target
Study Summary
This study is being conducted to determine if losartan, an angiotensin receptor blocker (ARB), is safe and effective in the treatment of posttraumatic stress disorder (PTSD) symptoms. The study is also intended to determine if certain genetic markers are useful in predicting PTSD symptom reduction with losartan. Approximately 160 subjects with chronic PTSD ages 18-65 will participate in this study across five sites. Subjects will be assigned by chance to take either flexibly dosed losartan (up to a maximum dosage of 100 mg) or placebo (which resembles the study drug but has no active ingredients), once a day for 10 weeks. Furthermore, it is hypothesized that CC homozygotes for rs4311 SNP in the ACE gene will have a superior response to losartan on PTSD symptoms compared to T carriers.
Interventions
- DRUG Placebo
- DRUG losartan
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 149 participants |
| Start Date | 2016-07-16 |
| Est. Completion | 2020-09-29 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02709018
The ClinicalTrials.gov registry entry for NCT02709018 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 149 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Diego, which has 775 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT02709018 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02709018 about?
NCT02709018 is a clinical study titled "A Controlled Trial of Losartan in Posttraumatic Stress Disorder". This study is being conducted to determine if losartan, an angiotensin receptor blocker (ARB), is safe and effective in the treatment of posttraumatic stress disorder (PTSD) symptoms. The study is also intended to determine if certain genetic markers are useful in predicting PTSD symptom reduction w...
What is the current status of trial NCT02709018?
This trial is currently completed. It is a NA study. The enrollment target is 149 participants. The study started on 2016-07-16. Estimated completion is 2020-09-29.
What interventions are being tested in trial NCT02709018?
The interventions under investigation include: Placebo (DRUG), losartan (DRUG).
Who is sponsoring clinical trial NCT02709018?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
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