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NCT02702180 · ClinicalTrials.gov registry record · Phase 2

Efficacy and Safety of Inhaled Molgramostim (rhGM-CSF) in Autoimmune Pulmonary Alveolar Proteinosis

A Phase 2 study, sponsored by Savara.

Completed
Registry status
Phase 2
Development phase
139
Enrollment target

NCT02702180 is a Phase 2 study that has completed, run by Savara. The registered enrollment target is 139 participants.

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The verdict

NCT02702180, a Phase 2 study, has completed, sponsored by Savara.

COMPLETED
Registry status
Phase 2
Development phase
139 participants
Enrollment target

Study Summary

This study evaluates inhaled molgramostim (recombinant human granulocyte macrophage-colony stimulating factor \[rhGM-CSF\]) in the treatment of autoimmune pulmonary alveolar proteinosis (aPAP) patients. A third of the patients will receive inhaled molgramostim once daily for 24 weeks, a third will receive inhaled molgramostim intermittently (7 days on, 7 days off) for 24 weeks and a third will receive inhaled matching placebo for 24 weeks.

Interventions

  • DRUG Placebo
  • DRUG Molgramostim
  • DEVICE PARI eFlow nebulizer system

Trial Details

FieldValue
Enrollment Target 139 participants
Start Date 2016-03-21
Est. Completion 2019-09-27
Phase Phase 2

Sponsor

Savara

5 total trials

What the Registry Record Tells You About NCT02702180

The ClinicalTrials.gov registry entry for NCT02702180 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 139 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Savara, which has 5 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT02702180 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02702180 about?

NCT02702180 is a clinical study titled "Efficacy and Safety of Inhaled Molgramostim (rhGM-CSF) in Autoimmune Pulmonary Alveolar Proteinosis". This study evaluates inhaled molgramostim (recombinant human granulocyte macrophage-colony stimulating factor \[rhGM-CSF\]) in the treatment of autoimmune pulmonary alveolar proteinosis (aPAP) patients. A third of the patients will receive inhaled molgramostim once daily for 24 weeks, a third will r...

What is the current status of trial NCT02702180?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 139 participants. The study started on 2016-03-21. Estimated completion is 2019-09-27.

What interventions are being tested in trial NCT02702180?

The interventions under investigation include: Placebo (DRUG), Molgramostim (DRUG), PARI eFlow nebulizer system (DEVICE).

Who is sponsoring clinical trial NCT02702180?

This trial is sponsored by Savara, which has 5 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.