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NCT02695160 · ClinicalTrials.gov registry record · Phase 1
Ascending Dose Study of Genome Editing by Zinc Finger Nuclease Therapeutic SB-FIX in Subjects With Severe Hemophilia B
A Phase 1 study, sponsored by Sangamo Therapeutics.
- Terminated
- Registry status
- Phase 1
- Development phase
- 1
- Enrollment target
NCT02695160 is a Phase 1 study that was terminated before completion, run by Sangamo Therapeutics. The registered enrollment target is 1 participants.
The verdict
NCT02695160, a Phase 1 study, was terminated before completion, sponsored by Sangamo Therapeutics.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 1 participants
- Enrollment target
Study Summary
The purpose of the study is to evaluate the safety, tolerability and effect on FIX antigen and activity levels of ascending doses of SB-FIX. SB-FIX is an intravenously delivered Zinc Finger Nuclease (ZFN) Therapeutic for genome editing. It inserts a correct copy of the Factor 9 gene into the albumin locus in hepatocytes with the goal of lifelong therapeutic production of the Factor IX clotting factor.
Interventions
- BIOLOGICAL SB-FIX
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1 participants |
| Start Date | 2016-11-15 |
| Est. Completion | 2021-04-19 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02695160
The ClinicalTrials.gov registry entry for NCT02695160 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 1 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Sangamo Therapeutics, which has 25 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which SB-FIX is the first listed.
NCT02695160 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02695160 about?
NCT02695160 is a clinical study titled "Ascending Dose Study of Genome Editing by Zinc Finger Nuclease Therapeutic SB-FIX in Subjects With Severe Hemophilia B". The purpose of the study is to evaluate the safety, tolerability and effect on FIX antigen and activity levels of ascending doses of SB-FIX. SB-FIX is an intravenously delivered Zinc Finger Nuclease (ZFN) Therapeutic for genome editing. It inserts a correct copy of the Factor 9 gene into the albumin...
What is the current status of trial NCT02695160?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 1 participants. The study started on 2016-11-15. Estimated completion is 2021-04-19.
What interventions are being tested in trial NCT02695160?
The interventions under investigation include: SB-FIX (BIOLOGICAL).
Who is sponsoring clinical trial NCT02695160?
This trial is sponsored by Sangamo Therapeutics, which has 25 total clinical trials registered on ClinicalTrials.gov.
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