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NCT02694068 · ClinicalTrials.gov registry record
Biological Determinants of Peritoneal Dialysis
A clinical trial, sponsored by University of Washington.
- Completed
- Registry status
- 4,865
- Enrollment target
NCT02694068 is a clinical trial that has completed, run by University of Washington. The registered enrollment target is 4,865 participants.
The verdict
NCT02694068 has completed, sponsored by University of Washington.
- COMPLETED
- Registry status
- 4,865 participants
- Enrollment target
Study Summary
Peritoneal Dialysis (PD) is a technique for treating kidney failure where fluid is instilled into the body's peritoneal cavity. Fluid and solutes travel across the peritoneal membrane, and the function of this membrane is critical to successful PD. Studies have shown that certain demographic and clinical variables explain a very small part of the variability in baseline function. This study will further explore the common genetic variants that determine the baseline peritoneal membrane function in patients starting treatment with PD and change in function upon treatment . This study will incorporate data from subjects' first ever peritoneal equilibrium test (PET), changes in the transfer of water across the peritoneal membrane over time, demographic information, and results from laboratory analysis of DNA, blood, and dialysate. The investigators hope that this study will provide information on the biological pathways that account for variability in the peritoneal membrane. This could ultimately lead to the development of biomarkers to identifying individuals at risk for decline in peritoneal membrane function over time and/or be used to identify novel therapeutic targets to preserve or enhance membrane function. Identifying the biological pathways will also increase the understanding of vascular biology, angiogenesis, and fibrosis that could be applied to other tissues and other diseases.
Interventions
- OTHER Peritoneal Equilibrium Test
- OTHER 4 hour dwell of 2.5/4.25% dextrose solution
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4,865 participants |
| Start Date | 2015-09-15 |
| Est. Completion | 2019-08-01 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02694068
The ClinicalTrials.gov registry entry for NCT02694068 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 4,865 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Washington, which has 1,048 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Peritoneal Equilibrium Test is the first listed.
NCT02694068 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02694068 about?
NCT02694068 is a clinical study titled "Biological Determinants of Peritoneal Dialysis". Peritoneal Dialysis (PD) is a technique for treating kidney failure where fluid is instilled into the body's peritoneal cavity. Fluid and solutes travel across the peritoneal membrane, and the function of this membrane is critical to successful PD. Studies have shown that certain demographic and cli...
What is the current status of trial NCT02694068?
This trial is currently completed. The enrollment target is 4,865 participants. The study started on 2015-09-15. Estimated completion is 2019-08-01.
What interventions are being tested in trial NCT02694068?
The interventions under investigation include: Peritoneal Equilibrium Test (OTHER), 4 hour dwell of 2.5/4.25% dextrose solution (OTHER).
Who is sponsoring clinical trial NCT02694068?
This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.
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