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NCT02694068 · ClinicalTrials.gov registry record
Biological Determinants of Peritoneal Dialysis
A clinical trial, sponsored by University of Washington.
- Completed
- Registry status
- 4,865
- Enrollment target
NCT02694068: Completed study, sponsored by University of Washington.
NCT02694068 is a clinical trial that has completed, run by University of Washington. The registered enrollment target is 4,865 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02694068 has completed, sponsored by University of Washington.
- COMPLETED
- Registry status
- 4,865 participants
- Enrollment target
Study Summary
Peritoneal Dialysis (PD) is a technique for treating kidney failure where fluid is instilled into the body's peritoneal cavity. Fluid and solutes travel across the peritoneal membrane, and the function of this membrane is critical to successful PD. Studies have shown that certain demographic and clinical variables explain a very small part of the variability in baseline function. This study will further explore the common genetic variants that determine the baseline peritoneal membrane function in patients starting treatment with PD and change in function upon treatment . This study will incorporate data from subjects' first ever peritoneal equilibrium test (PET), changes in the transfer of water across the peritoneal membrane over time, demographic information, and results from laboratory analysis of DNA, blood, and dialysate. The investigators hope that this study will provide information on the biological pathways that account for variability in the peritoneal membrane. This could ultimately lead to the development of biomarkers to identifying individuals at risk for decline in peritoneal membrane function over time and/or be used to identify novel therapeutic targets to preserve or enhance membrane function. Identifying the biological pathways will also increase the understanding of vascular biology, angiogenesis, and fibrosis that could be applied to other tissues and other diseases.
Primary Outcome
From Peritoneal Equilibration Test performed at the time of start of PD
Interventions
- OTHER Peritoneal Equilibrium Test
- OTHER 4 hour dwell of 2.5/4.25% dextrose solution
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4,865 participants |
| Start Date | 2015-09-15 |
| Est. Completion | 2019-08-01 |
What the finished NCT02694068 record still lists
NCT02694068 is an observational study that tracks outcomes without assigning an intervention. Its 4,865 participants enrollment target places it among the larger protocols in the corpus.
The record links to 0 conditions, and to 2 interventions - of which Peritoneal Equilibrium Test is the first listed.
NCT02694068 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02694068 about?
NCT02694068 is a clinical study titled "Biological Determinants of Peritoneal Dialysis". Peritoneal Dialysis (PD) is a technique for treating kidney failure where fluid is instilled into the body's peritoneal cavity. Fluid and solutes travel across the peritoneal membrane, and the function of this membrane is critical to successful PD. Studies have shown that certain demographic and cli...
What is the current status of trial NCT02694068?
This trial is currently completed. The enrollment target is 4,865 participants. The study started on 2015-09-15. Estimated completion is 2019-08-01.
What interventions are being tested in trial NCT02694068?
The interventions under investigation include: Peritoneal Equilibrium Test (OTHER), 4 hour dwell of 2.5/4.25% dextrose solution (OTHER).
Who is sponsoring clinical trial NCT02694068?
This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.
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