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COMPLETED Phase 4

Study to Evaluate the Effect of Secukinumab Compared to Placebo on Aortic Vascular Inflammation in Subjects With Moderate to Severe Plaque Psoriasis

NCT02690701 · View on ClinicalTrials.gov ↗

Study Summary

This study evaluated the effect of secukinumab compared to placebo on aortic vascular inflammation in adult patients who have moderate to severe plaque psoriasis that is poorly controlled by current psoriasis treatments.

Conditions Studied

Interventions

  • BIOLOGICAL Placebo
  • DRUG Secukinumab 300 mg

Study Locations (12)

California

  • Novartis Investigative Site — Los Angeles
  • Novartis Investigative Site — Santa Ana

New York

  • Novartis Investigative Site — Buffalo
  • Novartis Investigative Site — New York

Oregon

  • Novartis Investigative Site — Portland
  • Novartis Investigative Site — Portland

Texas

  • Novartis Investigative Site — Dallas
  • Novartis Investigative Site — Houston

Maryland

  • Novartis Investigative Site — Rockville

Missouri

  • Novartis Investigative Site — St Louis

Pennsylvania

  • Novartis Investigative Site — Exton

Utah

  • Novartis Investigative Site — Salt Lake City

Trial Details

FieldValue
Enrollment Target 91 participants
Start Date 2016-02-10
Est. Completion 2018-02-19
Phase Phase 4

Sponsor

Novartis Pharmaceuticals

792 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02690701

The ClinicalTrials.gov registry entry for NCT02690701 describes a study currently listed as completed. It is categorized as Phase 4, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 91 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novartis Pharmaceuticals, which has 792 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Chronic Plaque Psoriasis appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02690701 reports 12 study locations spanning 8 distinct geographic areas — top geographies include California, New York, Oregon. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02690701 about?

NCT02690701 is a clinical study titled "Study to Evaluate the Effect of Secukinumab Compared to Placebo on Aortic Vascular Inflammation in Subjects With Moderate to Severe Plaque Psoriasis". This study evaluated the effect of secukinumab compared to placebo on aortic vascular inflammation in adult patients who have moderate to severe plaque psoriasis that is poorly controlled by current psoriasis treatments.

What is the current status of trial NCT02690701?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 91 participants. The study started on 2016-02-10. Estimated completion is 2018-02-19.

What conditions does trial NCT02690701 study?

This clinical trial studies the following conditions: Chronic Plaque Psoriasis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02690701?

The interventions under investigation include: Placebo (BIOLOGICAL), Secukinumab 300 mg (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02690701?

This trial is sponsored by Novartis Pharmaceuticals, which has 792 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02690701 being conducted?

This trial has 12 study locations across California, Maryland, Missouri, New York, Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial