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NCT02680639 · ClinicalTrials.gov registry record · NA

The Use of High Frequency Oscillations With NIV in Hypercapnic COPD Participants

A NA study, sponsored by Philips Respironics.

Terminated
Registry status
NA
Development phase
10
Enrollment target

NCT02680639: Clinical Trial NA study, sponsored by Philips Respironics.

NCT02680639 is a NA study that was terminated before completion, run by Philips Respironics. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02680639, a NA study, was terminated before completion, sponsored by Philips Respironics.

TERMINATED
Registry status
NA
Development phase
10 participants
Enrollment target

Study Summary

Chronic Obstructive Pulmonary Disease (COPD) is a major cause of chronic morbidity and mortality throughout the world, being the fourth leading cause of death in the world. This study is designed to detect COPD participants with Expiratory Flow Limitation. EFL occurs when the airways become compressed which usually results when a pressure outside the airway exceeds the pressure inside the airway. Participants will undergo study eligibility procedures at visit 1. At visit 2 participants will undergo a baseline auto-EPAP (Expiratory Positive Airway Pressure) measurement. Then the order will be randomized to three different treatment methods. Between each treatment there will be at least a 10 minute washout period in order for CO2 to stabilize and return to baseline.

Primary Outcome

Transcutaneous carbon dioxide (TcCO2) monitoring is a non-invasive alternative to arterial blood sampling. Carbon Dioxide Levels will be measured for each participant as they complete each arm.

Interventions

  • DEVICE BiPAP Synchrony ventilator

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2015-11-13
Est. Completion 2016-08-24
Phase NA
Philips Respironics

35 total trials

Why NCT02680639 stopped before completion

NCT02680639 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which BiPAP Synchrony ventilator is the first listed.

NCT02680639 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02680639 about?

NCT02680639 is a clinical study titled "The Use of High Frequency Oscillations With NIV in Hypercapnic COPD Participants". Chronic Obstructive Pulmonary Disease (COPD) is a major cause of chronic morbidity and mortality throughout the world, being the fourth leading cause of death in the world. This study is designed to detect COPD participants with Expiratory Flow Limitation. EFL occurs when the airways become compres...

What is the current status of trial NCT02680639?

This trial is currently terminated. It is a NA study. The enrollment target is 10 participants. The study started on 2015-11-13. Estimated completion is 2016-08-24.

What interventions are being tested in trial NCT02680639?

The interventions under investigation include: BiPAP Synchrony ventilator (DEVICE).

Who is sponsoring clinical trial NCT02680639?

This trial is sponsored by Philips Respironics, which has 35 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02680639's enrollment target sits among peer trials

10 1927th of 2000 higher than 26 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02680639, the US trial registry maintained by the National Library of Medicine. NCT02680639 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.