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NCT02675452 · ClinicalTrials.gov registry record · Phase 1

AMG 176 First in Human Trial in Participants With Relapsed or Refractory Multiple Myeloma and Participants With Relapsed or Refractory Acute Myeloid Leukemia

A Phase 1 study, sponsored by Amgen.

Terminated
Registry status
Phase 1
Development phase
141
Enrollment target

NCT02675452 is a Phase 1 study that was terminated before completion, run by Amgen. The registered enrollment target is 141 participants.

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The verdict

NCT02675452, a Phase 1 study, was terminated before completion, sponsored by Amgen.

TERMINATED
Registry status
Phase 1
Development phase
141 participants
Enrollment target

Study Summary

The main objectives are to evaluate the safety and tolerability of AMG 176 monotherapy in participants with relapsed or refractory multiple myeloma and participants with relapsed or refractory acute myeloid leukemia.

Interventions

  • DRUG Azacitidine
  • DRUG Itraconazole
  • DRUG AMG 176

Trial Details

FieldValue
Enrollment Target 141 participants
Start Date 2016-06-13
Est. Completion 2024-05-27
Phase Phase 1

Sponsor

Amgen

558 total trials

What the Registry Record Tells You About NCT02675452

The ClinicalTrials.gov registry entry for NCT02675452 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 141 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Amgen, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Azacitidine is the first listed.

NCT02675452 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02675452 about?

NCT02675452 is a clinical study titled "AMG 176 First in Human Trial in Participants With Relapsed or Refractory Multiple Myeloma and Participants With Relapsed or Refractory Acute Myeloid Leukemia". The main objectives are to evaluate the safety and tolerability of AMG 176 monotherapy in participants with relapsed or refractory multiple myeloma and participants with relapsed or refractory acute myeloid leukemia.

What is the current status of trial NCT02675452?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 141 participants. The study started on 2016-06-13. Estimated completion is 2024-05-27.

What interventions are being tested in trial NCT02675452?

The interventions under investigation include: Azacitidine (DRUG), Itraconazole (DRUG), AMG 176 (DRUG).

Who is sponsoring clinical trial NCT02675452?

This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.