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NCT02663817 · ClinicalTrials.gov registry record · NA
DMH-Based Plan Evaluation and Inverse Optimization in Radiotherapy
A NA study, sponsored by University of Miami.
- Completed
- Registry status
- NA
- Development phase
- 52
- Enrollment target
NCT02663817: Completed NA study, sponsored by University of Miami.
NCT02663817 is a NA study that has completed, run by University of Miami. The registered enrollment target is 52 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02663817, a NA study, has completed, sponsored by University of Miami.
- COMPLETED
- Registry status
- NA
- Development phase
- 52 participants
- Enrollment target
Study Summary
The hypotheses of the study are as follows: * Mass-based inverse optimization in radiotherapy treatment planning will result in a reduction of normal tissue and organs at risk (OAR) doses for desired prescription therapeutic doses to the targets. * Dose-mass histograms (DMHs) may be more relevant to radiotherapy treatment planning and treatment plan assessment than the standard of care, realized through dose-volume histograms (DVHs)
Primary Outcome
The study is computational in nature. A new treatment planning paradigm is proposed, where from the newly proposed treatment plans, and the treatment plans generated with the standard of care, radiation doses to different organs and tissues would be derived. Radiotherapy toxicity (to healthy human tissue) is proportional to radiation dose - more radiation dose results in higher toxicity. Thereby, if radiation dose is decreased, the toxicity would also be decreased. The dosimetric differences whi
Interventions
- DEVICE CT Scan
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 52 participants |
| Start Date | 2015-06-19 |
| Est. Completion | 2019-04-04 |
| Phase | NA |
What the finished NCT02663817 record still lists
NCT02663817 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 52 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 1 intervention - of which CT Scan is the first listed.
NCT02663817 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02663817 about?
NCT02663817 is a clinical study titled "DMH-Based Plan Evaluation and Inverse Optimization in Radiotherapy". The hypotheses of the study are as follows: * Mass-based inverse optimization in radiotherapy treatment planning will result in a reduction of normal tissue and organs at risk (OAR) doses for desired prescription therapeutic doses to the targets. * Dose-mass histograms (DMHs) may be more relevant t...
What is the current status of trial NCT02663817?
This trial is currently completed. It is a NA study. The enrollment target is 52 participants. The study started on 2015-06-19. Estimated completion is 2019-04-04.
What interventions are being tested in trial NCT02663817?
The interventions under investigation include: CT Scan (DEVICE).
Who is sponsoring clinical trial NCT02663817?
This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02663817's enrollment target sits among peer trials
52 1272nd of 2000 higher than 722 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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