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NCT02660944 · ClinicalTrials.gov registry record · Phase 2

A Phase 2a of RSLV-132 in Subjects With Systemic Lupus Erythematosus (SLE)

A Phase 2 study, sponsored by Resolve Therapeutics.

Completed
Registry status
Phase 2
Development phase
64
Enrollment target

NCT02660944: Completed Phase 2 study, sponsored by Resolve Therapeutics.

NCT02660944 is a Phase 2 study that has completed, run by Resolve Therapeutics. The registered enrollment target is 64 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (52% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02660944, a Phase 2 study, has completed, sponsored by Resolve Therapeutics.

COMPLETED
Registry status
Phase 2
Development phase
64 participants
Enrollment target

Study Summary

This study evaluates the impact of 13 bi-weekly intravenous infusions of RSLV-132 on the cutaneous manifestations in subjects with systemic lupus erythematosus.

Primary Outcome

Mean change from baseline (from baseline to Day 85; or baseline to Day 169) in CLASI activity scores (Last Observation Carried Forward \[LOCF\] post censoring values). The CLASI is a single-page tool that separately quantifies disease activity and damage. For the activity score, points are given for the presence of erythema, scale, mucous membrane lesions, recent hair loss, and inflammatory alopecia. The total score represents the sum of the individual scores and ranges from 0 to 70. Higher sco

Interventions

  • DRUG Placebo
  • DRUG RSLV-132

Trial Details

FieldValue
Enrollment Target 64 participants
Start Date 2016-01-03
Est. Completion 2020-08-10
Phase Phase 2
Resolve Therapeutics

4 total trials

What the finished NCT02660944 record still lists

NCT02660944 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 64 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (52% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT02660944 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02660944 about?

NCT02660944 is a clinical study titled "A Phase 2a of RSLV-132 in Subjects With Systemic Lupus Erythematosus (SLE)". This study evaluates the impact of 13 bi-weekly intravenous infusions of RSLV-132 on the cutaneous manifestations in subjects with systemic lupus erythematosus.

What is the current status of trial NCT02660944?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 64 participants. The study started on 2016-01-03. Estimated completion is 2020-08-10.

What interventions are being tested in trial NCT02660944?

The interventions under investigation include: Placebo (DRUG), RSLV-132 (DRUG).

Who is sponsoring clinical trial NCT02660944?

This trial is sponsored by Resolve Therapeutics, which has 4 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02660944's enrollment target sits among peer trials

64 996th of 2000 higher than 992 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02660944, the US trial registry maintained by the National Library of Medicine. NCT02660944 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.