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NCT02644941 · ClinicalTrials.gov registry record · Phase 3

Comparison of the Human Acellular Vessel (HAV) With ePTFE Grafts as Conduits for Hemodialysis

A Phase 3 study, sponsored by Humacyte.

Completed
Registry status
Phase 3
Development phase
355
Enrollment target

NCT02644941: Completed Phase 3 study, sponsored by Humacyte.

NCT02644941 is a Phase 3 study that has completed, run by Humacyte. The registered enrollment target is 355 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (54% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02644941, a Phase 3 study, has completed, sponsored by Humacyte.

COMPLETED
Registry status
Phase 3
Development phase
355 participants
Enrollment target

Study Summary

The main purpose of this study is to compare the Human Acellular Vessel (HAV) with ePTFE grafts when used for hemodialysis access.

Primary Outcome

1. Defined as 'the interval from the time of access placement until access abandonment', i.e., patent with or without interventions (Sidawy et al. 2002). 2. "Abandonment" defined as no remaining segment of the study conduit was incorporated into the vascular access circuit used for dialysis (conversely, if some portion of the study conduit was still being used for dialysis it was not considered abandoned).

Interventions

  • BIOLOGICAL Human Acellular Vessel (HAV)
  • DEVICE ePTFE graft

Trial Details

FieldValue
Enrollment Target 355 participants
Start Date 2016-05-24
Est. Completion 2023-09
Phase Phase 3
Humacyte

6 total trials

What the finished NCT02644941 record still lists

NCT02644941 is an interventional study that assigns participants to a tested intervention. The registered 355 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (54% lower).

The record links to 0 conditions, and to 2 interventions - of which Human Acellular Vessel (HAV) is the first listed.

NCT02644941 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02644941 about?

NCT02644941 is a clinical study titled "Comparison of the Human Acellular Vessel (HAV) With ePTFE Grafts as Conduits for Hemodialysis". The main purpose of this study is to compare the Human Acellular Vessel (HAV) with ePTFE grafts when used for hemodialysis access.

What is the current status of trial NCT02644941?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 355 participants. The study started on 2016-05-24. Estimated completion is 2023-09.

What interventions are being tested in trial NCT02644941?

The interventions under investigation include: Human Acellular Vessel (HAV) (BIOLOGICAL), ePTFE graft (DEVICE).

Who is sponsoring clinical trial NCT02644941?

This trial is sponsored by Humacyte, which has 6 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02644941's enrollment target sits among peer trials

355 1025th of 2000 higher than 975 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02644941, the US trial registry maintained by the National Library of Medicine. NCT02644941 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.