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NCT02636283 · ClinicalTrials.gov registry record · Phase 2

Use of Entresto Sacubitril/Valsartan for the Treatment of Peripheral Arterial Disease

A Phase 2 study, sponsored by University of Minnesota.

Terminated
Registry status
Phase 2
Development phase
6
Enrollment target

NCT02636283: Clinical Trial Phase 2 study, sponsored by University of Minnesota.

NCT02636283 is a Phase 2 study that was terminated before completion, run by University of Minnesota. The registered enrollment target is 6 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02636283, a Phase 2 study, was terminated before completion, sponsored by University of Minnesota.

TERMINATED
Registry status
Phase 2
Development phase
6 participants
Enrollment target

Study Summary

This study proposes the use of Entresto (sacubitril/valsartan) to test the effects on pain free walking duration on patients with peripheral arterial disease, a condition caused by decreased blood flow to the muscles in the legs.

Primary Outcome

Time in minutes on a standardized treadmill test to initiation of pain and time until pain requires patient to stop walking

Interventions

  • DRUG Entresto
  • DRUG Placebo group

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2017-12-31
Est. Completion 2018-11-01
Phase Phase 2
University of Minnesota

966 total trials

Why NCT02636283 stopped before completion

NCT02636283 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 2 interventions - of which Entresto is the first listed.

NCT02636283 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02636283 about?

NCT02636283 is a clinical study titled "Use of Entresto Sacubitril/Valsartan for the Treatment of Peripheral Arterial Disease". This study proposes the use of Entresto (sacubitril/valsartan) to test the effects on pain free walking duration on patients with peripheral arterial disease, a condition caused by decreased blood flow to the muscles in the legs.

What is the current status of trial NCT02636283?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 6 participants. The study started on 2017-12-31. Estimated completion is 2018-11-01.

What interventions are being tested in trial NCT02636283?

The interventions under investigation include: Entresto (DRUG), Placebo group (DRUG).

Who is sponsoring clinical trial NCT02636283?

This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02636283's enrollment target sits among peer trials

6 1996th of 2000 higher than 1 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02636283, the US trial registry maintained by the National Library of Medicine. NCT02636283 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.