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NCT02626234 · ClinicalTrials.gov registry record · Phase 1

A Drug-drug Interaction (DDI) Study to Assess the Effect of INC280 on the Pharmacokinetics of Digoxin and Rosuvastatin in Patients With cMET-dysregulated Advanced Solid Tumors

A Phase 1 study of cMET-dysregulated Advanced Solid Tumors, sponsored by Novartis Pharmaceuticals.

Completed
Registry status
Phase 1
Development phase
32
Enrollment target
15
Study locations

NCT02626234 is a Phase 1 study of cMET-dysregulated Advanced Solid Tumors that has completed, run by Novartis Pharmaceuticals. The registered enrollment target is 32 participants. The trial reports 15 study locations across 7 states.

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The verdict

NCT02626234, a Phase 1 study of cMET-dysregulated Advanced Solid Tumors, has completed, sponsored by Novartis Pharmaceuticals.

COMPLETED
Registry status
Phase 1
Development phase
32 participants
Enrollment target
15
Study locations

Study Summary

the study aim to assess the effect of INC280 on the pharmacokinetics of digoxin and rosuvastatin in patients with cMET-dysregulated advanced solid tumors

Interventions

  • DRUG rosuvastatin
  • DRUG INC280
  • DRUG digoxin

Study Locations (15)

Other

  • Novartis Investigative Site - Vienna
  • Novartis Investigative Site - Brno
  • Novartis Investigative Site - Athens
  • Novartis Investigative Site - Bologna
  • Novartis Investigative Site - Naples
  • Novartis Investigative Site - Madrid
  • Novartis Investigative Site - Madrid
  • Novartis Investigative Site - London
  • Novartis Investigative Site - Manchester

Georgia

  • Emory University School of Medicine/Winship Cancer Institute Phase 1 Working Group - Atlanta

New Hampshire

  • Dartmouth Hitchcock Medical Center - Lebanon

Antwerpen

  • Novartis Investigative Site - Edegem

GR

  • Novartis Investigative Site - Ioannina

MI

  • Novartis Investigative Site - Milan

TO

  • Novartis Investigative Site - Candiolo

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 2015-12-08
Est. Completion 2017-04-28
Phase Phase 1

Sponsor

Novartis Pharmaceuticals

1,375 total trials

What the Registry Record Tells You About NCT02626234

The ClinicalTrials.gov registry entry for NCT02626234 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novartis Pharmaceuticals, which has 1,375 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with cMET-dysregulated Advanced Solid Tumors appearing as the primary indexed condition, and to 3 interventions - of which rosuvastatin is the first listed.

NCT02626234 reports 15 study locations spanning 7 distinct geographic areas - top geographies include Other, Georgia, New Hampshire.

Frequently Asked Questions

What is clinical trial NCT02626234 about?

NCT02626234 is a clinical study titled "A Drug-drug Interaction (DDI) Study to Assess the Effect of INC280 on the Pharmacokinetics of Digoxin and Rosuvastatin in Patients With cMET-dysregulated Advanced Solid Tumors". the study aim to assess the effect of INC280 on the pharmacokinetics of digoxin and rosuvastatin in patients with cMET-dysregulated advanced solid tumors

What is the current status of trial NCT02626234?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 32 participants. The study started on 2015-12-08. Estimated completion is 2017-04-28.

What conditions does trial NCT02626234 study?

This clinical trial studies the following conditions: cMET-dysregulated Advanced Solid Tumors.

What interventions are being tested in trial NCT02626234?

The interventions under investigation include: rosuvastatin (DRUG), INC280 (DRUG), digoxin (DRUG).

Who is sponsoring clinical trial NCT02626234?

This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02626234 being conducted?

This trial has 15 study locations across Georgia, New Hampshire, Antwerpen, GR, MI. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.