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NCT02589600 · ClinicalTrials.gov registry record · Phase 4
Zoledronic Acid for Osteoporotic Fracture Prevention (ZEST II)
A Phase 4 study, sponsored by Susan L. Greenspan.
- Completed
- Registry status
- Phase 4
- Development phase
- 310
- Enrollment target
NCT02589600: Completed Phase 4 study, sponsored by Susan L. Greenspan.
NCT02589600 is a Phase 4 study that has completed, run by Susan L. Greenspan. The registered enrollment target is 310 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02589600, a Phase 4 study, has completed, sponsored by Susan L. Greenspan.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 310 participants
- Enrollment target
Study Summary
The goal of this study is to perform the first fracture reduction clinical trial with a potent antiresorptive agent (intravenous zoledronic acid) in the most vulnerable long-term care population.
Primary Outcome
Number of fractures divided by number of person-years. Effectiveness of fracture reduction will be demonstrated by total non-traumatic incidental fractures (vertebral and nonvertebral \[identified by x-ray, CT, MRI, VFA imaging) except those viewed as severe trauma (fall from a height higher than a stool or chair or severe trauma other than a fall), cancer-related or fractures of the toes, finger or facial bones.
Interventions
- OTHER Saline
- DRUG Zoledronic acid
- DIETARY_SUPPLEMENT vitamin D
- DIETARY_SUPPLEMENT calcium
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 310 participants |
| Start Date | 2016-01 |
| Est. Completion | 2022-06-22 |
| Phase | Phase 4 |
What the finished NCT02589600 record still lists
NCT02589600 is an interventional study that assigns participants to a tested intervention. The registered 310 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (40% lower).
The record links to 0 conditions, and to 4 interventions - of which Saline is the first listed.
NCT02589600 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02589600 about?
NCT02589600 is a clinical study titled "Zoledronic Acid for Osteoporotic Fracture Prevention (ZEST II)". The goal of this study is to perform the first fracture reduction clinical trial with a potent antiresorptive agent (intravenous zoledronic acid) in the most vulnerable long-term care population.
What is the current status of trial NCT02589600?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 310 participants. The study started on 2016-01. Estimated completion is 2022-06-22.
What interventions are being tested in trial NCT02589600?
The interventions under investigation include: Saline (OTHER), Zoledronic acid (DRUG), vitamin D (DIETARY_SUPPLEMENT), calcium (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT02589600?
This trial is sponsored by Susan L. Greenspan, which has 6 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02589600's enrollment target sits among peer trials
310 263rd of 2000 higher than 1,738 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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