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NCT02586506 · ClinicalTrials.gov registry record · Phase 4

Study of the Ease of Use and Correct Use of Placebo ELLIPTA® Inhaler in Subjects With Asthma

A Phase 4 study, sponsored by GlaxoSmithKline.

Completed
Registry status
Phase 4
Development phase
259
Enrollment target

NCT02586506: Completed Phase 4 study, sponsored by GlaxoSmithKline.

NCT02586506 is a Phase 4 study that has completed, run by GlaxoSmithKline. The registered enrollment target is 259 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (50% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02586506, a Phase 4 study, has completed, sponsored by GlaxoSmithKline.

COMPLETED
Registry status
Phase 4
Development phase
259 participants
Enrollment target

Study Summary

Asthma is a chronic disease of the lungs characterized by airway inflammation, bronchoconstriction and increased airway responsiveness. Inhaled corticosteroids (ICS), alone or in combination with inhaled long-acting beta-adrenergic agonists (LABA), are considered a mainstay of treatment for treatment. For inhaled medications, the choice of inhalation device is an important consideration because an inadequate technique reduces the delivery of medicines and effects of inhalation. Therefore, the development of an easy-to-use inhaler that delivers the drug to the lungs effectively, is important. This study is designed to assess the correct use of the ELLIPTA inhaler in subjects with asthma and also to assess ease of use of the ELLIPTA inhaler, as rated by those subjects determined to be using the inhaler correctly. Study will be divided into two visits i.e. Screening/Visit 1 (day 1) and Visit 2 (Day 28 +/-2) with a phone call on Day 8+/-2 days of Visit 1 to assess safety. In this multi-center, single-arm, randomised (to receive one of two versions of the ELLIPTA inhaler Ease of Use questionnaires), open-label, placebo study, only subjects who are have never used the ELLIPTA inhaler before and have an established diagnosis of asthma and receiving asthma therapy and are able to demonstrate correct use of the ELLIPTA inhaler at Visit 1 will be considered eligible to participate in this study. Approximately 252 subjects will be screened with an expectation of 208 subjects completing the study while demonstrating correct ELLIPTA inhaler use at visit 2. ELLIPTA is a registered trademark of the GlaxoSmithKline Group of Companies.

Primary Outcome

Participants rated how easy it was to use the ELLIPTA inhaler, using a four-point Likert scale (1-very easy, 2-easy, 3-difficult, 4-very difficult). "Easy to use" was defined as the combination of an "easy" or "very easy" rating choice. The percentage was reported overall for the single treatment group along with a 95% confidence interval (CI) for the percentage calculated using the exact binomial distribution.

Interventions

  • OTHER Questionnaire
  • DRUG Placebo ELLIPTA inhaler

Trial Details

FieldValue
Enrollment Target 259 participants
Start Date 2015-10-01
Est. Completion 2016-02-04
Phase Phase 4
GlaxoSmithKline

1,345 total trials

What the finished NCT02586506 record still lists

NCT02586506 is an interventional study that assigns participants to a tested intervention. The registered 259 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (50% lower).

The record links to 0 conditions, and to 2 interventions - of which Questionnaire is the first listed.

NCT02586506 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02586506 about?

NCT02586506 is a clinical study titled "Study of the Ease of Use and Correct Use of Placebo ELLIPTA® Inhaler in Subjects With Asthma". Asthma is a chronic disease of the lungs characterized by airway inflammation, bronchoconstriction and increased airway responsiveness. Inhaled corticosteroids (ICS), alone or in combination with inhaled long-acting beta-adrenergic agonists (LABA), are considered a mainstay of treatment for treatmen...

What is the current status of trial NCT02586506?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 259 participants. The study started on 2015-10-01. Estimated completion is 2016-02-04.

What interventions are being tested in trial NCT02586506?

The interventions under investigation include: Questionnaire (OTHER), Placebo ELLIPTA inhaler (DRUG).

Who is sponsoring clinical trial NCT02586506?

This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02586506's enrollment target sits among peer trials

259 331st of 2000 higher than 1,669 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02586506, the US trial registry maintained by the National Library of Medicine. NCT02586506 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.