Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02581631 · ClinicalTrials.gov registry record · Phase 1

An Investigational Immuno-therapy Safety and Effectiveness Study of Nivolumab in Combination With Brentuximab Vedotin to Treat Non-Hodgkin Lymphomas

A Phase 1 study, sponsored by Bristol-Myers Squibb.

Completed
Registry status
Phase 1
Development phase
145
Enrollment target

NCT02581631 is a Phase 1 study that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 145 participants.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT02581631, a Phase 1 study, has completed, sponsored by Bristol-Myers Squibb.

COMPLETED
Registry status
Phase 1
Development phase
145 participants
Enrollment target

Study Summary

The purpose of this study is to determine whether Nivolumab, in combination with brentuximab vedotin, is safe and effective in patients with certain subtypes of non-Hodgkin's lymphomas with CD30 expression that have not responded to treatment or have come back. The subtypes we are studying are Diffuse Large B-Cell Lymphoma (DLBCL), Peripheral T-Cell Lymphoma (PTCL), Cutaneous T-Cell Lymphoma (CTCL), Primary Mediastinal Large B-Cell Lymphoma (PMBL) and Mediastinal Gray Zone Lymphoma (MGZL).

Interventions

  • BIOLOGICAL Nivolumab
  • DRUG Brentuximab Vedotin

Trial Details

FieldValue
Enrollment Target 145 participants
Start Date 2016-02-11
Est. Completion 2022-02-07
Phase Phase 1

Sponsor

Bristol-Myers Squibb

1,025 total trials

What the Registry Record Tells You About NCT02581631

The ClinicalTrials.gov registry entry for NCT02581631 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 145 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Bristol-Myers Squibb, which has 1,025 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Nivolumab is the first listed.

NCT02581631 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02581631 about?

NCT02581631 is a clinical study titled "An Investigational Immuno-therapy Safety and Effectiveness Study of Nivolumab in Combination With Brentuximab Vedotin to Treat Non-Hodgkin Lymphomas". The purpose of this study is to determine whether Nivolumab, in combination with brentuximab vedotin, is safe and effective in patients with certain subtypes of non-Hodgkin's lymphomas with CD30 expression that have not responded to treatment or have come back. The subtypes we are studying are Diffu...

What is the current status of trial NCT02581631?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 145 participants. The study started on 2016-02-11. Estimated completion is 2022-02-07.

What interventions are being tested in trial NCT02581631?

The interventions under investigation include: Nivolumab (BIOLOGICAL), Brentuximab Vedotin (DRUG).

Who is sponsoring clinical trial NCT02581631?

This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.