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NCT02574663 · ClinicalTrials.gov registry record · Phase 1

TGR-1202 Alone and in Combination With Either Nab-paclitaxel + Gemcitabine or With FOLFOX in Patients With Select Relapsed or Refractory Solid Tumors

A Phase 1 study, sponsored by TG Therapeutics.

Completed
Registry status
Phase 1
Development phase
66
Enrollment target

NCT02574663: Completed Phase 1 study, sponsored by TG Therapeutics.

NCT02574663 is a Phase 1 study that has completed, run by TG Therapeutics. The registered enrollment target is 66 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (10% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02574663, a Phase 1 study, has completed, sponsored by TG Therapeutics.

COMPLETED
Registry status
Phase 1
Development phase
66 participants
Enrollment target

Study Summary

This is a Phase 1 multi-center study to assess the safety and efficacy of TGR-1202 as a single agent or in combination with nab-paclitaxel + gemcitabine or with FOLFOX in patients with select relapsed or refractory solid tumors.

Primary Outcome

To determine the incidence of adverse events, any potential abnormal laboratory results and any dose-limiting toxicities.

Interventions

  • DRUG TGR-1202
  • DRUG nab-paclitaxel + gemcitabine
  • DRUG Oxaliplatin + Folinic acid + Fluorouracil
  • DRUG Oxaliplatin + Folinic acid + Fluorouracil + Bevacizumab

Trial Details

FieldValue
Enrollment Target 66 participants
Start Date 2015-09-11
Est. Completion 2018-08
Phase Phase 1
TG Therapeutics

33 total trials

What the finished NCT02574663 record still lists

NCT02574663 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 66 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (10% higher).

The record links to 0 conditions, and to 4 interventions - of which TGR-1202 is the first listed.

NCT02574663 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02574663 about?

NCT02574663 is a clinical study titled "TGR-1202 Alone and in Combination With Either Nab-paclitaxel + Gemcitabine or With FOLFOX in Patients With Select Relapsed or Refractory Solid Tumors". This is a Phase 1 multi-center study to assess the safety and efficacy of TGR-1202 as a single agent or in combination with nab-paclitaxel + gemcitabine or with FOLFOX in patients with select relapsed or refractory solid tumors.

What is the current status of trial NCT02574663?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 66 participants. The study started on 2015-09-11. Estimated completion is 2018-08.

What interventions are being tested in trial NCT02574663?

The interventions under investigation include: TGR-1202 (DRUG), nab-paclitaxel + gemcitabine (DRUG), Oxaliplatin + Folinic acid + Fluorouracil (DRUG), Oxaliplatin + Folinic acid + Fluorouracil + Bevacizumab (DRUG).

Who is sponsoring clinical trial NCT02574663?

This trial is sponsored by TG Therapeutics, which has 33 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02574663's enrollment target sits among peer trials

66 786th of 2000 higher than 1,203 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02574663, the US trial registry maintained by the National Library of Medicine. NCT02574663 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.