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NCT02569398 · ClinicalTrials.gov registry record · Phase 2

An Efficacy and Safety Study of Atabecestat in Participants Who Are Asymptomatic at Risk for Developing Alzheimer's Dementia

A Phase 2 study, sponsored by Janssen Research & Development.

Terminated
Registry status
Phase 2
Development phase
557
Enrollment target

NCT02569398 is a Phase 2 study that was terminated before completion, run by Janssen Research & Development. The registered enrollment target is 557 participants.

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The verdict

NCT02569398, a Phase 2 study, was terminated before completion, sponsored by Janssen Research & Development.

TERMINATED
Registry status
Phase 2
Development phase
557 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate whether treatment with atabecestat slows cognitive decline compared with placebo treatment, as measured by a composite cognitive measure, the Preclinical Alzheimer Cognitive Composite (PACC), in amyloid-positive participants who are asymptomatic at risk for developing Alzheimer's dementia.

Interventions

  • DRUG Placebo
  • DRUG Atabecestat, 5 mg
  • DRUG Atabecestat, 25 mg

Trial Details

FieldValue
Enrollment Target 557 participants
Start Date 2015-10-29
Est. Completion 2018-12-20
Phase Phase 2

Sponsor

Janssen Research & Development

593 total trials

What the Registry Record Tells You About NCT02569398

The ClinicalTrials.gov registry entry for NCT02569398 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 557 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Janssen Research & Development, which has 593 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT02569398 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02569398 about?

NCT02569398 is a clinical study titled "An Efficacy and Safety Study of Atabecestat in Participants Who Are Asymptomatic at Risk for Developing Alzheimer's Dementia". The purpose of this study is to evaluate whether treatment with atabecestat slows cognitive decline compared with placebo treatment, as measured by a composite cognitive measure, the Preclinical Alzheimer Cognitive Composite (PACC), in amyloid-positive participants who are asymptomatic at risk for d...

What is the current status of trial NCT02569398?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 557 participants. The study started on 2015-10-29. Estimated completion is 2018-12-20.

What interventions are being tested in trial NCT02569398?

The interventions under investigation include: Placebo (DRUG), Atabecestat, 5 mg (DRUG), Atabecestat, 25 mg (DRUG).

Who is sponsoring clinical trial NCT02569398?

This trial is sponsored by Janssen Research & Development, which has 593 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.