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NCT02567448 · ClinicalTrials.gov registry record · NA
Pathophysiology of the Upper Airway in Patients With COPD and Concomitant OSA
A NA study, sponsored by University of California, San Diego.
- Terminated
- Registry status
- NA
- Development phase
- 24
- Enrollment target
NCT02567448: Clinical Trial NA study, sponsored by University of California, San Diego.
NCT02567448 is a NA study that was terminated before completion, run by University of California, San Diego. The registered enrollment target is 24 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02567448, a NA study, was terminated before completion, sponsored by University of California, San Diego.
- TERMINATED
- Registry status
- NA
- Development phase
- 24 participants
- Enrollment target
Study Summary
The purpose of study is to evaluate the physiologic effects of pulmonary tissue/structural changes associated with COPD and upper airway inflammation on upper airway collapsibility. Upper airway collapsibility is closely associated with development of obstructive sleep apnea (OSA), which is a common disease characterized by repetitive collapse of upper airway during sleep, leading to hypoxemia and arousal. OSA has important neurocognitive and cardiovascular consequences, especially in patients with COPD. Participants in this research study will undergo two overnight sleep studies (PSGs), pulmonary function test, and CT scan of the upper airway and chest. The first sleep study will evaluate the sleep breathing disorder and the second sleep study will measure the upper airway collapsibility, called critical closing pressure (Pcrit). Pcrit is measured by a modified continuous positive airway pressure (CPAP) machine which can provide a wide range of pressures between 20 and -20 cmH2O in order to modify upper airway pressure.
Primary Outcome
Measured during overnight sleep study
Interventions
- OTHER Sleep and pulmonary physiologic measurements
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2015-07-01 |
| Est. Completion | 2016-08-11 |
| Phase | NA |
Why NCT02567448 stopped before completion
NCT02567448 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which Sleep and pulmonary physiologic measurements is the first listed.
NCT02567448 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02567448 about?
NCT02567448 is a clinical study titled "Pathophysiology of the Upper Airway in Patients With COPD and Concomitant OSA". The purpose of study is to evaluate the physiologic effects of pulmonary tissue/structural changes associated with COPD and upper airway inflammation on upper airway collapsibility. Upper airway collapsibility is closely associated with development of obstructive sleep apnea (OSA), which is a common...
What is the current status of trial NCT02567448?
This trial is currently terminated. It is a NA study. The enrollment target is 24 participants. The study started on 2015-07-01. Estimated completion is 2016-08-11.
What interventions are being tested in trial NCT02567448?
The interventions under investigation include: Sleep and pulmonary physiologic measurements (OTHER).
Who is sponsoring clinical trial NCT02567448?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02567448's enrollment target sits among peer trials
24 1736th of 2000 higher than 246 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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