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NCT02559024 · ClinicalTrials.gov registry record · Phase 1

Anti-OX40 Antibody (MEDI6469) in Patients With Metastatic Colorectal Cancer

A Phase 1 study, sponsored by Providence Health & Services.

Terminated
Registry status
Phase 1
Development phase
4
Enrollment target

NCT02559024: Clinical Trial Phase 1 study, sponsored by Providence Health & Services.

NCT02559024 is a Phase 1 study that was terminated before completion, run by Providence Health & Services. The registered enrollment target is 4 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02559024, a Phase 1 study, was terminated before completion, sponsored by Providence Health & Services.

TERMINATED
Registry status
Phase 1
Development phase
4 participants
Enrollment target

Study Summary

This study will test the ability of an immune modulator, anti-OX40 (MEDI6469) to alter the immune cell environment within colorectal cancer metastases. The drug will be administered to patients before surgical treatment.

Primary Outcome

Patients are seen at least 7 times in clinic and have 3 physical exams and provide interim medical history four times to identify potential side-effects or complications related to the study drug.

Interventions

  • DRUG MEDI6469

Trial Details

FieldValue
Enrollment Target 4 participants
Start Date 2016-03-14
Est. Completion 2018-10
Phase Phase 1
Providence Health & Services

69 total trials

Why NCT02559024 stopped before completion

NCT02559024 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% lower).

The record links to 0 conditions, and to 1 intervention - of which MEDI6469 is the first listed.

NCT02559024 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02559024 about?

NCT02559024 is a clinical study titled "Anti-OX40 Antibody (MEDI6469) in Patients With Metastatic Colorectal Cancer". This study will test the ability of an immune modulator, anti-OX40 (MEDI6469) to alter the immune cell environment within colorectal cancer metastases. The drug will be administered to patients before surgical treatment.

What is the current status of trial NCT02559024?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 4 participants. The study started on 2016-03-14. Estimated completion is 2018-10.

What interventions are being tested in trial NCT02559024?

The interventions under investigation include: MEDI6469 (DRUG).

Who is sponsoring clinical trial NCT02559024?

This trial is sponsored by Providence Health & Services, which has 69 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02559024's enrollment target sits among peer trials

4 1995th of 2000 higher than 2 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02559024, the US trial registry maintained by the National Library of Medicine. NCT02559024 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.