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NCT02558010 · ClinicalTrials.gov registry record · Phase 3
Perioperative Methadone Use to Decrease Opioid Requirement in Pediatric Spinal Fusion Patients
A Phase 3 study, sponsored by Medical College of Wisconsin.
- Completed
- Registry status
- Phase 3
- Development phase
- 58
- Enrollment target
NCT02558010: Completed Phase 3 study, sponsored by Medical College of Wisconsin.
NCT02558010 is a Phase 3 study that has completed, run by Medical College of Wisconsin. The registered enrollment target is 58 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02558010, a Phase 3 study, has completed, sponsored by Medical College of Wisconsin.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 58 participants
- Enrollment target
Study Summary
Acute pain management following major surgical procedures in pediatric patients continues to be a challenge, especially after extensive posterior spine fusions. Spine surgery is particularly traumatic, initiating pain in both peripheral and central pathways. While the standard management of post-surgical pain involves a multimodal approach, opioids provide the predominant benefit. However, opioid use is associated with many adverse effects, including nausea, constipation, and pruritus. Perioperative methadone may decrease total opioid consumption and adverse effects as well as improve satisfaction with pain management after scoliosis repair.
Primary Outcome
Total amount of opioids consumed during the first 72 hours after surgery.
Interventions
- DRUG Methadone
- OTHER Normal Saline
- DRUG Morphine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 58 participants |
| Start Date | 2016-02-01 |
| Est. Completion | 2023-01-01 |
| Phase | Phase 3 |
What the finished NCT02558010 record still lists
NCT02558010 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 58 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 3 interventions - of which Methadone is the first listed.
NCT02558010 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02558010 about?
NCT02558010 is a clinical study titled "Perioperative Methadone Use to Decrease Opioid Requirement in Pediatric Spinal Fusion Patients". Acute pain management following major surgical procedures in pediatric patients continues to be a challenge, especially after extensive posterior spine fusions. Spine surgery is particularly traumatic, initiating pain in both peripheral and central pathways. While the standard management of post-su...
What is the current status of trial NCT02558010?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 58 participants. The study started on 2016-02-01. Estimated completion is 2023-01-01.
What interventions are being tested in trial NCT02558010?
The interventions under investigation include: Methadone (DRUG), Normal Saline (OTHER), Morphine (DRUG).
Who is sponsoring clinical trial NCT02558010?
This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02558010's enrollment target sits among peer trials
58 1825th of 2000 higher than 174 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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