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NCT02554591 · ClinicalTrials.gov registry record
Genomic Landscape of Ceritinib
A clinical trial, sponsored by Washington University School of Medicine.
- Terminated
- Registry status
- 6
- Enrollment target
NCT02554591: Clinical Trial study, sponsored by Washington University School of Medicine.
NCT02554591 is a clinical trial that was terminated before completion, run by Washington University School of Medicine. The registered enrollment target is 6 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02554591 was terminated before completion, sponsored by Washington University School of Medicine.
- TERMINATED
- Registry status
- 6 participants
- Enrollment target
Study Summary
The investigators propose to conduct a retrospective study of single agent ceritinib in patients with previously untreated anaplastic lymphoma kinase (ALK) rearranged adenocarcinoma of the lung with the sole purpose of characterizing the genomic landscape before ceritinib and at the time of disease progression.
Primary Outcome
* The investigators will compare tumor sequencing prior to ceritinib treatment to the time of disease progression to see if the genetic sequencing changed between pre-treatment and progression. * The investigators plan to conduct exome and transcriptome sequencing of tumor before therapy with certitinib and at the time of relapse. In addition, exome sequencing of peripheral blood DNA will be done (for germline). Given the complexities of genomic analyses of paired samples in the face of limited
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2015-09-16 |
| Est. Completion | 2018-02-28 |
Why NCT02554591 stopped before completion
NCT02554591 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 6 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT02554591 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02554591 about?
NCT02554591 is a clinical study titled "Genomic Landscape of Ceritinib". The investigators propose to conduct a retrospective study of single agent ceritinib in patients with previously untreated anaplastic lymphoma kinase (ALK) rearranged adenocarcinoma of the lung with the sole purpose of characterizing the genomic landscape before ceritinib and at the time of disease ...
What is the current status of trial NCT02554591?
This trial is currently terminated. The enrollment target is 6 participants. The study started on 2015-09-16. Estimated completion is 2018-02-28.
Who is sponsoring clinical trial NCT02554591?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
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