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NCT02549716 · ClinicalTrials.gov registry record · Phase 4
Clinical, Pharmacological and Molecular Effects of IV and Oral Acetaminophen in Adults With aSAH
A Phase 4 study, sponsored by Milton S. Hershey Medical Center.
- Terminated
- Registry status
- Phase 4
- Development phase
- 3
- Enrollment target
NCT02549716: Clinical Trial Phase 4 study, sponsored by Milton S. Hershey Medical Center.
NCT02549716 is a Phase 4 study that was terminated before completion, run by Milton S. Hershey Medical Center. The registered enrollment target is 3 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02549716, a Phase 4 study, was terminated before completion, sponsored by Milton S. Hershey Medical Center.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 3 participants
- Enrollment target
Study Summary
This study compares the bioavailability of IV and PO acetaminophen in both blood and the cerebrospinal fluid (CSF) of patients following subarachnoid hemorrhage. The study will also compare the temperature and levels of inflammatory cytokines in both blood and CSF of patients treated with IV and PO acetaminophen.
Primary Outcome
Patients in both IV and PO groups will have samples taken from their Cerebral Spinal Fluid (CSF) and blood at the above times after acetaminophen is administered for the first time. They will then have additional samples taken every 24 hours following the time of first drug administration for 14 days. Patients will also have a sample collected every 35 hours (1 hour before the 6th loading dose) to determine the steady state level of acetaminophen.
Interventions
- DRUG IV acetaminophen
- DRUG Oral acetaminophen
- DRUG Oral placebo
- DRUG IV placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2017-01-05 |
| Est. Completion | 2018-06-08 |
| Phase | Phase 4 |
Why NCT02549716 stopped before completion
NCT02549716 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 4 interventions - of which IV acetaminophen is the first listed.
NCT02549716 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02549716 about?
NCT02549716 is a clinical study titled "Clinical, Pharmacological and Molecular Effects of IV and Oral Acetaminophen in Adults With aSAH". This study compares the bioavailability of IV and PO acetaminophen in both blood and the cerebrospinal fluid (CSF) of patients following subarachnoid hemorrhage. The study will also compare the temperature and levels of inflammatory cytokines in both blood and CSF of patients treated with IV and PO ...
What is the current status of trial NCT02549716?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 3 participants. The study started on 2017-01-05. Estimated completion is 2018-06-08.
What interventions are being tested in trial NCT02549716?
The interventions under investigation include: IV acetaminophen (DRUG), Oral acetaminophen (DRUG), Oral placebo (DRUG), IV placebo (DRUG).
Who is sponsoring clinical trial NCT02549716?
This trial is sponsored by Milton S. Hershey Medical Center, which has 396 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02549716's enrollment target sits among peer trials
3 1995th of 2000 higher than 3 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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