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NCT02547766 · ClinicalTrials.gov registry record · Phase 1
Interleukin-1 Receptor Antagonist for the Treatment of Heart Failure in Patients With Left Ventricular Assist Devices
A Phase 1 study of Heart Failure, sponsored by University of Utah.
- Completed
- Registry status
- Phase 1
- Development phase
- 10
- Enrollment target
- 1
- Study location
NCT02547766: Completed Phase 1 study of Heart Failure, sponsored by University of Utah.
NCT02547766 is a Phase 1 study of Heart Failure that has completed, run by University of Utah. The registered enrollment target is 10 participants, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02547766, a Phase 1 study of Heart Failure, has completed, sponsored by University of Utah.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
Heart failure remains a major cause of morbidity and mortality. Many patients with heart failure receive support from a left ventricular assist device (LVAD) at some point in the course of their disease. Some of these LVAD patients experience a durable recovery after ventricular unloading with an LVAD, which may be associated with inhibition of inflammatory cytokines. This small pilot study aims to determine the biologic and clinical efficacy of an interleukin-1 receptor antagonist (Anakinra) at inducing myocardial recovery in patients supported with left ventricular assist devices.
Primary Outcome
The primary endpoint was a reduction in inflammatory markers, specifically C-reactive protein (CRP).
Conditions Studied
Interventions
- DRUG Anakinra
Study Locations (1)
Utah
- University of Utah - Salt Lake City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2015-04 |
| Est. Completion | 2016-12 |
| Phase | Phase 1 |
What the finished NCT02547766 record still lists
NCT02547766 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (100% lower).
The record links to 1 condition, with Heart Failure appearing as the primary indexed condition, and to 1 intervention - of which Anakinra is the first listed.
NCT02547766 reports a single indexed study location in Utah.
Frequently Asked Questions
What is clinical trial NCT02547766 about?
NCT02547766 is a clinical study titled "Interleukin-1 Receptor Antagonist for the Treatment of Heart Failure in Patients With Left Ventricular Assist Devices". Heart failure remains a major cause of morbidity and mortality. Many patients with heart failure receive support from a left ventricular assist device (LVAD) at some point in the course of their disease. Some of these LVAD patients experience a durable recovery after ventricular unloading with an LV...
What is the current status of trial NCT02547766?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2015-04. Estimated completion is 2016-12.
What conditions does trial NCT02547766 study?
This clinical trial studies the following conditions: Heart Failure.
What interventions are being tested in trial NCT02547766?
The interventions under investigation include: Anakinra (DRUG).
Who is sponsoring clinical trial NCT02547766?
This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02547766 being conducted?
This trial has 1 study location across Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Heart Failure
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02547766's enrollment target sits among peer trials
10 383rd of 397 higher than 7 of 397 other Heart Failure trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Heart Failure trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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