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NCT02546986 · ClinicalTrials.gov registry record · Phase 2

Safety and Efficacy Study of CC-486 With MK-3475 to Treat Locally Advanced or Metastatic Non-small Cell Lung Cancer

A Phase 2 study, sponsored by Celgene.

Completed
Registry status
Phase 2
Development phase
100
Enrollment target

NCT02546986 is a Phase 2 study that has completed, run by Celgene. The registered enrollment target is 100 participants.

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The verdict

NCT02546986, a Phase 2 study, has completed, sponsored by Celgene.

COMPLETED
Registry status
Phase 2
Development phase
100 participants
Enrollment target

Study Summary

The purpose of this study is to determine whether the combination therapy of CC-486 (oral azacitidine) and pembrolizumab provides improved patient outcomes compared to pembrolizumab alone in patients with previously treated locally advanced or metastatic non-small cell lung cancer.

Interventions

  • DRUG Pembrolizumab
  • DRUG Placebo
  • DRUG CC-486

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2015-10-09
Est. Completion 2025-07-07
Phase Phase 2

Sponsor

Celgene

308 total trials

What the Registry Record Tells You About NCT02546986

The ClinicalTrials.gov registry entry for NCT02546986 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Celgene, which has 308 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Pembrolizumab is the first listed.

NCT02546986 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02546986 about?

NCT02546986 is a clinical study titled "Safety and Efficacy Study of CC-486 With MK-3475 to Treat Locally Advanced or Metastatic Non-small Cell Lung Cancer". The purpose of this study is to determine whether the combination therapy of CC-486 (oral azacitidine) and pembrolizumab provides improved patient outcomes compared to pembrolizumab alone in patients with previously treated locally advanced or metastatic non-small cell lung cancer.

What is the current status of trial NCT02546986?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 100 participants. The study started on 2015-10-09. Estimated completion is 2025-07-07.

What interventions are being tested in trial NCT02546986?

The interventions under investigation include: Pembrolizumab (DRUG), Placebo (DRUG), CC-486 (DRUG).

Who is sponsoring clinical trial NCT02546986?

This trial is sponsored by Celgene, which has 308 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.