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NCT02543268 · ClinicalTrials.gov registry record · Phase 3
A Study to Evaluate the Immunogenicity, Safety and Tolerability of Ad26.ZEBOV and MVA-BN-Filo in Healthy Adult Participants
A Phase 3 study, sponsored by Crucell Holland.
- Completed
- Registry status
- Phase 3
- Development phase
- 329
- Enrollment target
NCT02543268: Completed Phase 3 study, sponsored by Crucell Holland.
NCT02543268 is a Phase 3 study that has completed, run by Crucell Holland. The registered enrollment target is 329 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (57% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02543268, a Phase 3 study, has completed, sponsored by Crucell Holland.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 329 participants
- Enrollment target
Study Summary
The purpose of this study is to compare the humoral immune response induced by 3 different batches of Ad26.ZEBOV as measured by enzyme - linked immunosorbent assay (ELISA) against the Ebola virus (EBOV) GP (Glycoprotein) at 56 days post prime.
Primary Outcome
The humoral immune response will be assessed by enzyme-linked immunosorbent assay (ELISA) binding antibody
Interventions
- BIOLOGICAL Placebo
- BIOLOGICAL MVA-BN-Filo
- BIOLOGICAL Ad26.ZEBOV-Batch #1
- BIOLOGICAL Ad26.ZEBOV-Batch #2
- BIOLOGICAL Ad26.ZEBOV-Batch #3
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 329 participants |
| Start Date | 2015-09-21 |
| Est. Completion | 2016-07-20 |
| Phase | Phase 3 |
What the finished NCT02543268 record still lists
NCT02543268 is an interventional study that assigns participants to a tested intervention. The registered 329 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (57% lower).
The record links to 0 conditions, and to 5 interventions - of which Placebo is the first listed.
NCT02543268 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02543268 about?
NCT02543268 is a clinical study titled "A Study to Evaluate the Immunogenicity, Safety and Tolerability of Ad26.ZEBOV and MVA-BN-Filo in Healthy Adult Participants". The purpose of this study is to compare the humoral immune response induced by 3 different batches of Ad26.ZEBOV as measured by enzyme - linked immunosorbent assay (ELISA) against the Ebola virus (EBOV) GP (Glycoprotein) at 56 days post prime.
What is the current status of trial NCT02543268?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 329 participants. The study started on 2015-09-21. Estimated completion is 2016-07-20.
What interventions are being tested in trial NCT02543268?
The interventions under investigation include: Placebo (BIOLOGICAL), MVA-BN-Filo (BIOLOGICAL), Ad26.ZEBOV-Batch #1 (BIOLOGICAL), Ad26.ZEBOV-Batch #2 (BIOLOGICAL), Ad26.ZEBOV-Batch #3 (BIOLOGICAL).
Who is sponsoring clinical trial NCT02543268?
This trial is sponsored by Crucell Holland, which has 10 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02543268's enrollment target sits among peer trials
329 1074th of 2000 higher than 927 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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