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NCT02533674 · ClinicalTrials.gov registry record · Phase 1

Multicenter, Open-label, Clinical and Pharmacokinetic Study of PM060184 in Combination With Gemcitabine in Selected Patients With Advanced Solid Tumors

A Phase 1 study, sponsored by PharmaMar.

Completed
Registry status
Phase 1
Development phase
57
Enrollment target

NCT02533674 is a Phase 1 study that has completed, run by PharmaMar. The registered enrollment target is 57 participants.

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The verdict

NCT02533674, a Phase 1 study, has completed, sponsored by PharmaMar.

COMPLETED
Registry status
Phase 1
Development phase
57 participants
Enrollment target

Study Summary

Prospective, open-label, dose-ranging, uncontrolled phase I study with escalating doses of PM060184 in combination with gemcitabine in selected patients with advanced solid tumors. The study objectives are: To determine the MTD and the RD of PM060184 in combination with gemcitabine in selected patients with advanced solid tumors. To characterize the safety profile and feasibility of this combination in this study population. To characterize the pharmacokinetics of this combination and to detect major drug-drug PK interactions. To obtain preliminary information on the clinical antitumor activity of this combination.

Interventions

  • DRUG Gemcitabine plus PM060184

Trial Details

FieldValue
Enrollment Target 57 participants
Start Date 2014-12-12
Est. Completion 2019-07-11
Phase Phase 1

Sponsor

PharmaMar

32 total trials

What the Registry Record Tells You About NCT02533674

The ClinicalTrials.gov registry entry for NCT02533674 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 57 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is PharmaMar, which has 32 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Gemcitabine plus PM060184 is the first listed.

NCT02533674 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02533674 about?

NCT02533674 is a clinical study titled "Multicenter, Open-label, Clinical and Pharmacokinetic Study of PM060184 in Combination With Gemcitabine in Selected Patients With Advanced Solid Tumors". Prospective, open-label, dose-ranging, uncontrolled phase I study with escalating doses of PM060184 in combination with gemcitabine in selected patients with advanced solid tumors. The study objectives are: To determine the MTD and the RD of PM060184 in combination with gemcitabine in selected pat...

What is the current status of trial NCT02533674?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 57 participants. The study started on 2014-12-12. Estimated completion is 2019-07-11.

What interventions are being tested in trial NCT02533674?

The interventions under investigation include: Gemcitabine plus PM060184 (DRUG).

Who is sponsoring clinical trial NCT02533674?

This trial is sponsored by PharmaMar, which has 32 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.