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NCT02527681 · ClinicalTrials.gov registry record · Phase 1

Pharmacokinetics and Safety of Ceftobiprole in Neonates and Infants up to 3 Months Treated With Systemic Antibiotics

A Phase 1 study, sponsored by Basilea Pharmaceutica.

Terminated
Registry status
Phase 1
Development phase
15
Enrollment target

NCT02527681: Clinical Trial Phase 1 study, sponsored by Basilea Pharmaceutica.

NCT02527681 is a Phase 1 study that was terminated before completion, run by Basilea Pharmaceutica. The registered enrollment target is 15 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02527681, a Phase 1 study, was terminated before completion, sponsored by Basilea Pharmaceutica.

TERMINATED
Registry status
Phase 1
Development phase
15 participants
Enrollment target

Study Summary

This study characterized the pharmacokinetics and safety of a single dose of ceftobiprole in neonates and infants aged ≤ 3 months.

Primary Outcome

The maximum observed plasma concentration (Cmax)

Interventions

  • DRUG Ceftobiprole medocaril

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2016-11-22
Est. Completion 2020-02-25
Phase Phase 1
Basilea Pharmaceutica

21 total trials

Why NCT02527681 stopped before completion

NCT02527681 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower).

The record links to 0 conditions, and to 1 intervention - of which Ceftobiprole medocaril is the first listed.

NCT02527681 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02527681 about?

NCT02527681 is a clinical study titled "Pharmacokinetics and Safety of Ceftobiprole in Neonates and Infants up to 3 Months Treated With Systemic Antibiotics". This study characterized the pharmacokinetics and safety of a single dose of ceftobiprole in neonates and infants aged ≤ 3 months.

What is the current status of trial NCT02527681?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 15 participants. The study started on 2016-11-22. Estimated completion is 2020-02-25.

What interventions are being tested in trial NCT02527681?

The interventions under investigation include: Ceftobiprole medocaril (DRUG).

Who is sponsoring clinical trial NCT02527681?

This trial is sponsored by Basilea Pharmaceutica, which has 21 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02527681's enrollment target sits among peer trials

15 1798th of 2000 higher than 157 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02527681, the US trial registry maintained by the National Library of Medicine. NCT02527681 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.