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NCT02525796 · ClinicalTrials.gov registry record · Phase 2
Evaluating Alternative Medical Therapies in Primary Hyperparathyroidism
A Phase 2 study, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- Phase 2
- Development phase
- 69
- Enrollment target
NCT02525796: Completed Phase 2 study, sponsored by Brigham and Women's Hospital.
NCT02525796 is a Phase 2 study that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 69 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (48% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02525796, a Phase 2 study, has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 69 participants
- Enrollment target
Study Summary
This study will evaluate whether blocking the mineralocorticoid receptor, alone, or in combination with the calcimimetic cinacalcet, can lower parathyroid hormone and calcium levels in primary hyperparathyroidism.
Primary Outcome
Change in circulating PTH levels before and after 4 weeks of double-blinded intervention when compared to placebo
Interventions
- DRUG Placebo
- DRUG Cinacalcet
- DRUG eplerenone
- DRUG amiloride
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 69 participants |
| Start Date | 2016-01 |
| Est. Completion | 2021-10-02 |
| Phase | Phase 2 |
What the finished NCT02525796 record still lists
NCT02525796 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 69 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (48% lower).
The record links to 0 conditions, and to 4 interventions - of which Placebo is the first listed.
NCT02525796 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02525796 about?
NCT02525796 is a clinical study titled "Evaluating Alternative Medical Therapies in Primary Hyperparathyroidism". This study will evaluate whether blocking the mineralocorticoid receptor, alone, or in combination with the calcimimetic cinacalcet, can lower parathyroid hormone and calcium levels in primary hyperparathyroidism.
What is the current status of trial NCT02525796?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 69 participants. The study started on 2016-01. Estimated completion is 2021-10-02.
What interventions are being tested in trial NCT02525796?
The interventions under investigation include: Placebo (DRUG), Cinacalcet (DRUG), eplerenone (DRUG), amiloride (DRUG).
Who is sponsoring clinical trial NCT02525796?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02525796's enrollment target sits among peer trials
69 965th of 2000 higher than 1,034 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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