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NCT02515227 · ClinicalTrials.gov registry record · Phase 1
Safety Study of a Helper Peptide Vaccine Plus Pembrolizumab
A Phase 1 study, sponsored by Craig L Slingluff, Jr.
- Completed
- Registry status
- Phase 1
- Development phase
- 22
- Enrollment target
NCT02515227: Completed Phase 1 study, sponsored by Craig L Slingluff, Jr.
NCT02515227 is a Phase 1 study that has completed, run by Craig L Slingluff, Jr. The registered enrollment target is 22 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (63% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02515227, a Phase 1 study, has completed, sponsored by Craig L Slingluff, Jr.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 22 participants
- Enrollment target
Study Summary
This study evaluates whether it is safe to administer a peptide vaccine in combination with pembrolizumab. This study will also evaluate the effects of the combination of the peptide vaccine and pembrolizumab on the immune system. The investigators will monitor these effects by performing tests in the laboratory on participants' blood, a lymph node, and tumor samples.
Primary Outcome
Number of participants with dose-limiting toxicities on treatment with combination of pembrolizumab and 6MHP.
Interventions
- DRUG Pembrolizumab
- BIOLOGICAL 6MHP
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2016-10-06 |
| Est. Completion | 2020-03-14 |
| Phase | Phase 1 |
What the finished NCT02515227 record still lists
NCT02515227 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (63% lower).
The record links to 0 conditions, and to 2 interventions - of which Pembrolizumab is the first listed.
NCT02515227 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02515227 about?
NCT02515227 is a clinical study titled "Safety Study of a Helper Peptide Vaccine Plus Pembrolizumab". This study evaluates whether it is safe to administer a peptide vaccine in combination with pembrolizumab. This study will also evaluate the effects of the combination of the peptide vaccine and pembrolizumab on the immune system. The investigators will monitor these effects by performing tests in t...
What is the current status of trial NCT02515227?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 22 participants. The study started on 2016-10-06. Estimated completion is 2020-03-14.
What interventions are being tested in trial NCT02515227?
The interventions under investigation include: Pembrolizumab (DRUG), 6MHP (BIOLOGICAL).
Who is sponsoring clinical trial NCT02515227?
This trial is sponsored by Craig L Slingluff, Jr, which has 23 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02515227's enrollment target sits among peer trials
22 1601st of 2000 higher than 386 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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